Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18209347 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPK1LMNAGAARXFP1 | |
| SCHEMBL20252170 | 0.81 | L3MBTL1 (0.41) | SMN1; SMN2MAPK1LMNAL3MBTL1KDM4E | |
| SCHEMBL20252174 | 0.81 | L3MBTL1 (0.41) | SMN1; SMN2MAPK1LMNAL3MBTL1KDM4E | |
| SCHEMBL10100811 | 0.79 | KDM4E (0.47) | SMN1; SMN2MAPK1LMNARXFP1L3MBTL1 | |
| SCHEMBL14039032 | 0.78 | ENPP2 (0.49) | SMN1; SMN2MAPK1LMNAGAARXFP1 | |
| SCHEMBL16521616 | 0.76 | IDO1 (0.47) | SMN1; SMN2MAPK1LMNAL3MBTL1KDM4E | |
| SCHEMBL28001656 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1LMNAL3MBTL1KDM4E | |
| SCHEMBL31495214 | 0.75 | TUBB4A (0.49) | SMN1; SMN2MAPK1L3MBTL1KDM4EATM | |
| SCHEMBL11978644 | 0.74 | KDM4E (0.50) | SMN1; SMN2LMNAL3MBTL1KDM4EATM | |
| SCHEMBL10066241 | 0.73 | KDM4E (0.53) | SMN1; SMN2LMNAL3MBTL1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130020563-A1 | POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2013-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130020563-A1 | POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | KCNC1, EED, BMI1 | SMN1; SMN2 4618/4885MAPK1 2186/4885LMNA 693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.