SCHEMBL10101151

SCHEMBL10101151

O=C(CSC(=O)c1ccccc1)NCCCNC(=O)CSC(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.56
ALDH1A1 P00352 2/20 0.56
MAPT P10636 2/20 0.56
HTT P42858 1/20 0.56
GPR139 Q6DWJ6 1/20 0.55
HDAC3 O15379 3/20 0.49
HDAC4 P56524 3/20 0.49
HDAC1 Q13547 3/20 0.49
HDAC7 Q8WUI4 3/20 0.49
HDAC2 Q92769 3/20 0.49
HDAC10 Q969S8 3/20 0.49
HDAC11 Q96DB2 3/20 0.49
HDAC8 Q9BY41 3/20 0.49
HDAC6 Q9UBN7 3/20 0.49
HDAC9 Q9UKV0 3/20 0.49
HDAC5 Q9UQL6 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.46
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16135523 0.87 KMT2A (0.50) KMT2AALDH1A1MAPTHTTGPR139
SCHEMBL8123492 0.87 KMT2A (0.54) KMT2AALDH1A1MAPTHTTGPR139
SCHEMBL16089522 0.85 KMT2A (0.48) KMT2AALDH1A1MAPTHTTGPR139
SCHEMBL16089628 0.83 KMT2A (0.49) KMT2AALDH1A1MAPTHTTGPR139
SCHEMBL10309087 0.83 KMT2A (0.51) KMT2AALDH1A1MAPTHTTGPR139
SCHEMBL8595095 0.83 GPR139 (0.55) KMT2AALDH1A1MAPTHTTGPR139
SCHEMBL8387484 0.83 GPR139 (0.55) KMT2AALDH1A1MAPTHTTGPR139
SCHEMBL19636689 0.82 NAAA (0.51) KMT2AALDH1A1MAPTHTTGPR139
SCHEMBL16089621 0.81 KMT2A (0.47) KMT2AALDH1A1MAPTHTTGPR139
SCHEMBL23612753 0.80 CXCR4 (0.52) KMT2AALDH1A1MAPTHTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9074264-B2 Method for recovering precious metal from solution containing precious metal ions, extracting agent or adsorbent used therefor, and back-extracting agent or desorbent TOSOH CORPORATION (JP) 2015-07-07 US disclosed
US-9074264-B2 Method for recovering precious metal from solution containing precious metal ions, extracting agent or adsorbent used therefor, and back-extracting agent or desorbent TOSOH CORPORATION (JP) 2015-07-07 US disclosed
EP-2659964-A1 METHOD FOR COLLECTING PRECIOUS METALS FROM SOLUTION CONTAINING PRECIOUS METAL IONS, EXTRACTANT OR ADSORBENT USED THEREFOR, AND BACK EXTRACTANT OR DESORBENT Tosoh Corporation (JP) 2013-11-06 EP disclosed
US-20130281726-A1 METHOD FOR RECOVERING PRECIOUS METAL FROM SOLUTION CONTAINING PRECIOUS METAL IONS, EXTRACTING AGENT OR ADSORBENT USED THEREFOR, AND BACK-EXTRACTING AGENT OR DESORBENT TOSOH CORPORATION (JP) 2013-10-24 US disclosed
US-20130281726-A1 METHOD FOR RECOVERING PRECIOUS METAL FROM SOLUTION CONTAINING PRECIOUS METAL IONS, EXTRACTING AGENT OR ADSORBENT USED THEREFOR, AND BACK-EXTRACTING AGENT OR DESORBENT TOSOH CORPORATION (JP) 2013-10-24 US disclosed
US-20120164039-A1 PALLADIUM ION ADSORBENT AND METHODS FOR SEPARATING AND RECOVERING PALLADIUM USING IT TOSOH CORPORATION (JP) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120164039-A1 PALLADIUM ION ADSORBENT AND METHODS FOR SEPARATING AND RECOVERING PALLADIUM USING IT PDCD10, PARK7, CCR10 KMT2A 643/4885ALDH1A1 601/4885MAPT 4679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.