Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL865412 | 1.00 | KMT2A (0.39) | KMT2ADPP4MAPK1GPR119MC4R | |
| SCHEMBL865411 | 1.00 | KMT2A (0.39) | KMT2ADPP4MAPK1GPR119MC4R | |
| SCHEMBL864975 | 0.93 | DPP4 (0.37) | KMT2ADPP4MAPK1GPR119MC4R | |
| SCHEMBL10101176 | 0.93 | DPP4 (0.37) | KMT2ADPP4MAPK1GPR119MC4R | |
| SCHEMBL864976 | 0.93 | DPP4 (0.37) | KMT2ADPP4MAPK1GPR119MC4R | |
| SCHEMBL864977 | 0.93 | DPP4 (0.37) | KMT2ADPP4MAPK1GPR119MC4R | |
| SCHEMBL864520 | 0.91 | GPR119 (0.42) | KMT2ADPP4MAPK1GPR119PABPC1 | |
| SCHEMBL864521 | 0.91 | GPR119 (0.42) | KMT2ADPP4MAPK1GPR119PABPC1 | |
| SCHEMBL10101193 | 0.89 | ALDH1A1 (0.41) | KMT2ADPP4MAPK1GPR119MC4R | |
| SCHEMBL865185 | 0.89 | ALDH1A1 (0.41) | KMT2ADPP4MAPK1GPR119MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077793-A1 | Compounds for the Treatment of Metabolic Disorders | PROSIDION LIMITED (GB) | 2012-03-29 | — | — | US | disclosed |
| US-20120077793-A1 | Compounds for the Treatment of Metabolic Disorders | PROSIDION LIMITED (GB) | 2012-03-29 | — | — | US | disclosed |
| WO-2010103333-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077793-A1 | Compounds for the Treatment of Metabolic Disorders | GPR119, GPR132, FFAR2 | KMT2A 2799/4885DPP4 217/4885MAPK1 3641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.