Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 17/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.69 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.69 |
| ▸ | CNR1 | P21554 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | CNR2 | P34972 | 1/20 | 0.69 |
| ▸ | HTR2B | P41595 | 1/20 | 0.69 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010723 | 0.90 | FAAH (0.56) | FAAHCYP3A4CYP2D6GABRA1ADRA2C | |
| SCHEMBL1009416 | 0.89 | CYP3A4 (0.56) | FAAHCYP3A4CYP2D6GABRA1ADRA2C | |
| SCHEMBL1011894 | 0.89 | CYP3A4 (0.56) | FAAHCYP3A4CYP2D6GABRA1ADRA2C | |
| SCHEMBL1014193 | 0.89 | FAAH (0.55) | FAAHCYP3A4CYP2D6GABRA1ADRA2C | |
| SCHEMBL27094615 | 0.88 | CYP3A4 (0.55) | FAAHCYP3A4CYP2D6GABRA1ADRA2C | |
| SCHEMBL1010369 | 0.88 | FAAH (0.53) | FAAHCYP3A4CYP2D6GABRA1ADRA2C | |
| SCHEMBL30657590 | 0.88 | FAAH (0.71) | FAAHCYP3A4CYP2D6GABRA1ADRA2C | |
| SCHEMBL27094617 | 0.88 | FAAH (0.71) | FAAHCYP3A4CYP2D6GABRA1ADRA2C | |
| SCHEMBL1012251 | 0.88 | FAAH (0.54) | FAAHCYP3A4CYP2D6GABRA1ADRA2C | |
| SCHEMBL14810692 | 0.88 | FAAH (0.68) | FAAHCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11998538-B2 | Piperidine urea derivatives as soluble epoxide hydrolase inhibitors | NEUROPN THERAPEUTICS (US) | 2024-06-04 | — | — | US | disclosed |
| US-20240024313-A1 | BIARYL ETHER UREA COMPOUNDS | Jazz Pharmaceuticals Therapeutics, Inc. | 2024-01-25 | — | — | US | disclosed |
| US-20240024313-A1 | BIARYL ETHER UREA COMPOUNDS | Jazz Pharmaceuticals Therapeutics, Inc. | 2024-01-25 | — | — | US | disclosed |
| US-8044052-B2 | Inhibitors of fatty acid amide hydrolase; N-pyridin-3-yl-4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzylidene)piperidine-1-carboxamide; elevate brain anandamide levels; pain, urinary incontinence, cognitive disorders, anxiety, depression, sleeping, eating, movement disorders, glaucoma, psoriasis | PFIZER INC. (US) | 2011-10-25 | — | — | US | disclosed |
| EP-2076508-B1 | BIARYL ETHER UREA COMPOUNDS | PFIZER PROD INC (US) | 2011-01-05 | — | — | EP | disclosed |
| EP-2076508-A2 | BIARYL ETHER UREA COMPOUNDS | Pfizer Products Inc. (US) | 2009-07-08 | — | — | EP | disclosed |
| US-20080261941-A1 | Biaryl Ether Urea Compounds | Jazz Pharmaceuticals Therapeutics, Inc. | 2008-10-23 | — | — | US | disclosed |
| WO-2008047229-A2 | BIARYL ETHER UREA COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240024313-A1 | BIARYL ETHER UREA COMPOUNDS | FAAH, FAAH2, FAH | FAAH 1/4885CYP3A4 138/4885CYP2D6 41/4885 |
| US-20080261941-A1 | Biaryl Ether Urea Compounds | FAAH, FAAH2, LIPC | FAAH 1/4885CYP3A4 303/4885CYP2D6 292/4885 |
| US-11998538-B2 | Piperidine urea derivatives as soluble epoxide hydrolase inhibitors | EPHX1, EPHX2, HPGDS | FAAH 8/4885CYP3A4 712/4885CYP2D6 1859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.