SCHEMBL10101586

SCHEMBL10101586

CC(C)(C)NCC(=O)NC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
KDM1A O60341 1/20 0.39
POLB P06746 2/20 0.38
HDAC2 Q92769 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 2/20 0.37
NPC1 O15118 2/20 0.37
GAA P10253 1/20 0.37
DPP4 P27487 3/20 0.36
DPP8 Q6V1X1 1/20 0.36
DPP9 Q86TI2 1/20 0.36
TSHR P16473 1/20 0.35
HPGD P15428 1/20 0.35
EPHX1 P07099 1/20 0.34
LMNA P02545 2/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6281966 0.80 ALDH1A1 (0.62) POLBALDH1A1DPP4DPP8DPP9
SCHEMBL6276761 0.80 PIK3CD (0.57) MAPTPOLBHDAC2ALDH1A1DPP4
SCHEMBL13596286 0.79 MAPT (0.39) MAPTKDM1APOLBHDAC2SMN1; SMN2
SCHEMBL3404618 0.79 MCL1 (0.37) ALDH1A1DPP4DPP8DPP9LMNA
SCHEMBL18026348 0.77 ALDH1A1 (0.47) MAPTPOLBHDAC2SMN1; SMN2ALDH1A1
SCHEMBL12556801 0.77 MAPT (0.38) MAPTKDM1APOLBHDAC2SMN1; SMN2
SCHEMBL4083881 0.77 CTSD (0.42) ALDH1A1GAADPP4DPP8DPP9
Hydrochloric Acid SCHEMBL30225271 0.77 MAPT (0.38) MAPTKDM1APOLBHDAC2SMN1; SMN2
SCHEMBL21706037 0.77 KDM1A (0.33) MAPTKDM1APOLBHDAC2SMN1; SMN2
SCHEMBL10245280 0.75 MCL1 (0.41) ALDH1A1GAADPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12019371-B2 Photosensitive composition, film, color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2024-06-25 US disclosed
EP-4175001-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION BATTERY Mitsubishi Chemical Corporation (JP) 2023-05-03 EP disclosed
US-20230046457-A1 BRUTON'S TYROSINE KINASE INHIBITORS BIOGEN MA INC. 2023-02-16 US disclosed
US-20220332970-A1 PHOTOSENSITIVE COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-10-20 US disclosed
US-20210278761-A1 COLORING PHOTOSENSITIVE COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-09-09 US disclosed
US-20210223436-A1 STRUCTURAL BODY, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-07-22 US disclosed
US-20210088902-A1 PHOTOSENSITIVE COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-03-25 US disclosed
US-9790229-B2 Bruton's tyrosine kinase inhibitors SUNESIS PHARMACEUTICALS, INC. (US) 2017-10-17 US disclosed
US-9624166-B2 Tetracycline compounds TETRAPHASE PHARMACEUTICALS, INC. (US) 2017-04-18 US disclosed
US-8367654-B2 8-AZA tetracycline compounds TETRAPHASE PHARMACEUTICALS, INC. (US) 2013-02-05 US disclosed
US-20120108569-A1 8-AZA Tetracycline Compounds TETRAPHASE PHARMACEUTICALS, INC. 2012-05-03 US disclosed
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230046457-A1 BRUTON'S TYROSINE KINASE INHIBITORS BTK, ABL1, SYK MAPT 4120/4885KDM1A 1668/4885POLB 1897/4885
US-20120108569-A1 8-AZA Tetracycline Compounds TET1, TET3, HDAC8 MAPT 921/4885KDM1A 127/4885POLB 1713/4885
US-20090281292-A1 10a-Azalide Compound IL17A, AZI2, HDAC9 MAPT 4302/4885KDM1A 124/4885POLB 3348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.