Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GRK2 | P25098 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24709973 | 0.83 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EL3MBTL1EPHX1 | |
| SCHEMBL8736888 | 0.80 | ALDH1A1 (0.69) | ALDH1A1HPGDKDM4EL3MBTL1EPHX1 | |
| SCHEMBL10101586 | 0.80 | MAPT (0.39) | ALDH1A1HPGDDPP4DPP8DPP9 | |
| SCHEMBL19245501 | 0.78 | ALDH1A1 (0.60) | ALDH1A1HPGDL3MBTL1LMNAMEN1 | |
| SCHEMBL15498405 | 0.77 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EL3MBTL1EPHX1 | |
| SCHEMBL5907624 | 0.76 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EL3MBTL1LMNA | |
| SCHEMBL21162583 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HPGDL3MBTL1LMNAMEN1 | |
| SCHEMBL15961859 | 0.73 | ALDH1A1 (0.60) | ALDH1A1HPGDKDM4EL3MBTL1EPHX1 | |
| SCHEMBL25997951 | 0.73 | ALDH1A1 (0.60) | ALDH1A1HPGDKDM4EL3MBTL1EPHX1 | |
| SCHEMBL15498413 | 0.73 | ALDH1A1 (0.55) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841703-B2 | Open chain alkoxyamine compounds and their use as polymerization regulators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-01-11 | — | — | US | disclosed |
| EP-1100772-B1 | OPEN CHAIN ALKOXYAMINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS | CIBA SC HOLDING AG (CH) | 2004-04-14 | — | — | EP | disclosed |
| US-20030125489-A1 | Open chain alkoxyamine compounds and their use as polymerization regulators | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |
| US-6518326-B1 | Open chain alkoxyamine compounds and their use as polymerization regulators | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-02-11 | — | — | US | disclosed |
| EP-1100772-A1 | OPEN CHAIN ALKOXYAMINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS | Ciba SC Holding AG (CH) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000007981-A1 | OPEN CHAIN ALKOXYAMINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125489-A1 | Open chain alkoxyamine compounds and their use as polymerization regulators | ALOX5, PTGER1, ALOX12 | ALDH1A1 290/4885HPGD 1718/4885DPP4 4818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.