Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30592933 | 0.81 | HSD17B10 (0.45) | POLBNAMPTHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL20669147 | 0.80 | POLB (0.56) | POLBNAMPTHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL20669138 | 0.80 | CYP2D6 (0.48) | POLBNAMPTALDH1A1CYP1A2USP2 | |
| Hydrochloric Acid SCHEMBL30184174 | 0.79 | CYP2D6 (0.47) | POLBNAMPTALDH1A1CYP1A2USP2 | |
| SCHEMBL22043622 | 0.77 | HSD17B10 (0.51) | POLBNAMPTHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL20669176 | 0.77 | HSD17B10 (0.51) | POLBNAMPTHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL10101693 | 0.77 | POLB (0.50) | POLBBAZ2BUSP2 | |
| SCHEMBL2593681 | 0.76 | SMN1; SMN2 (0.45) | NAMPTHSD17B10ALDH1A1CYP1A2USP2 | |
| SCHEMBL21358327 | 0.75 | CHRNB2 (0.47) | NAMPTHSD17B10ALDH1A1CYP1A2USP2 | |
| SCHEMBL30059414 | 0.75 | NAMPT (0.36) | NAMPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083476-A1 | HETEROARYL-SUBSTITUTED SPIROCYCLIC DIAMINE UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083476-A1 | HETEROARYL-SUBSTITUTED SPIROCYCLIC DIAMINE UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, DBH | POLB 1736/4885NAMPT 497/4885HSD17B10 949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.