SCHEMBL10106296

SCHEMBL10106296

Cc1ccc(-c2ccc(CCCC(P(=O)(O)O)P(=O)(O)O)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 7/20 0.56
FDPS P14324 3/20 0.43
ENPP2 Q13822 1/20 0.41
S1PR2 O95136 1/20 0.41
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41
LPAR2 Q9HBW0 1/20 0.41
GGPS1 O95749 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9661622 0.87 FDFT1 (0.53) FDFT1FDPSENPP2S1PR2S1PR1
SCHEMBL9544118 0.85 FDFT1 (0.71) FDFT1
SCHEMBL9663262 0.84 FDFT1 (0.53) FDFT1
SCHEMBL3885276 0.83 FDFT1 (0.51) FDFT1ENPP2S1PR2S1PR1S1PR3
SCHEMBL1237801 0.82 FDFT1 (0.61) FDFT1
SCHEMBL9662849 0.81 FDPS (0.62) FDFT1FDPSENPP2S1PR2S1PR1
SCHEMBL9632927 0.81 FDPS (0.57) FDFT1FDPSENPP2S1PR2S1PR1
SCHEMBL9663350 0.81 FDFT1 (0.50) FDFT1S1PR2S1PR1S1PR3
SCHEMBL9663772 0.81 FDFT1 (0.47) FDFT1FDPSS1PR2S1PR1S1PR3
SCHEMBL413324 0.81 FDFT1 (0.60) FDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120022024-A1 ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022024-A1 ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS CUTA, MMP8, CLPP FDFT1 1987/4885FDPS 2463/4885ENPP2 418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.