Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218531 | 0.71 | HTR2C (0.39) | HTR2C | |
| SCHEMBL1008924 | 0.68 | TAAR1 (0.38) | HTR2A | |
| SCHEMBL3826696 | 0.67 | GRM5 (0.30) | — | |
| SCHEMBL4752992 | 0.65 | KIF11 (0.41) | — | |
| SCHEMBL6222347 | 0.65 | KIF11 (0.41) | — | |
| SCHEMBL5313362 | 0.64 | MEN1 (0.37) | — | |
| SCHEMBL4750486 | 0.64 | GRM2 (0.42) | — | |
| SCHEMBL8128825 | 0.64 | CES1 (0.31) | — | |
| SCHEMBL4748741 | 0.63 | CYP3A4 (0.30) | — | |
| SCHEMBL5045425 | 0.63 | TMPRSS4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268273-A1 | SMALL-MOLECULE MODULATORS OF TRP-P8 ACTIVITY | DENDREON CORPORATION (US) | 2011-01-05 | — | — | EP | claimed |
| WO-2009067410-A1 | SMALL-MOLECULE MODULATORS OF TRP-P8 ACTIVITY | DENDREON CORPORATION (US) | 2009-05-28 | — | — | WO | claimed |
| EP-2268273-A1 | SMALL-MOLECULE MODULATORS OF TRP-P8 ACTIVITY | DENDREON CORPORATION (US) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009067410-A1 | SMALL-MOLECULE MODULATORS OF TRP-P8 ACTIVITY | DENDREON CORPORATION (US) | 2009-05-28 | — | — | WO | disclosed |