Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6222347 | 1.00 | KIF11 (0.41) | KIF11JUNNFKB1NFKB2RELA | |
| SCHEMBL4750486 | 0.87 | GRM2 (0.42) | KIF11JUNNFKB1NFKB2RELA | |
| SCHEMBL2429783 | 0.82 | JUN (0.44) | KIF11JUNNFKB1NFKB2RELA | |
| SCHEMBL6221498 | 0.81 | KIF11 (0.40) | KIF11NFKB1NFKB2RELAKMT2A | |
| SCHEMBL3755963 | 0.78 | AURKB (0.42) | KIF11PARP1 | |
| SCHEMBL6264592 | 0.77 | CA1 (0.40) | PARP1KMT2AKDM4E | |
| SCHEMBL5313362 | 0.76 | MEN1 (0.37) | JUNNFKB1NFKB2RELATDP2 | |
| SCHEMBL7003987 | 0.75 | ALDH1A1 (0.44) | KIF11KMT2AHTT | |
| SCHEMBL473854 | 0.73 | TGM2 (0.44) | METAP2TDP2KMT2A | |
| SCHEMBL1695075 | 0.73 | CA9 (0.38) | PARP1KMT2AHSD17B10HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |