Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | BIRC5 | O15392 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045425 | 0.86 | TMPRSS4 (0.39) | MEN1KMT2ATMPRSS4BIRC5CYP1A2 | |
| SCHEMBL4752992 | 0.76 | KIF11 (0.41) | KMT2ANFKB1PARP1TDP2JUN | |
| SCHEMBL6222347 | 0.76 | KIF11 (0.41) | KMT2ANFKB1PARP1TDP2JUN | |
| SCHEMBL4750486 | 0.75 | GRM2 (0.42) | MEN1KMT2ANFKB1PARP1TDP2 | |
| SCHEMBL6218531 | 0.66 | HTR2C (0.39) | MEN1KMT2ACYP1A2NOTUM | |
| SCHEMBL1765579 | 0.63 | HSD17B10 (0.49) | MEN1KMT2ATOP2AHSP90AA1CYP1A2 | |
| SCHEMBL863774 | 0.62 | CES2 (0.55) | MEN1KMT2ATMPRSS4NFKB1CES2 | |
| SCHEMBL2429783 | 0.62 | JUN (0.44) | KMT2ANFKB1PARP1PARP10TDP2 | |
| SCHEMBL5194204 | 0.61 | TDP2 (0.59) | MEN1KMT2ANFKB1CYP3A4PARP1 | |
| SCHEMBL31586640 | 0.61 | TDP2 (0.59) | MEN1KMT2ANFKB1CYP3A4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |