SCHEMBL1010709

SCHEMBL1010709

OCC1C2CN(Cc3ccccc3)CC12

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FUCA1 P04066 2/20 0.58
GBA1 P04062 1/20 0.57
SIGMAR1 Q99720 2/20 0.50
S1PR1 P21453 1/20 0.50
S1PR5 Q9H228 1/20 0.50
DRD2 P14416 4/20 0.48
DRD3 P35462 4/20 0.48
ALDH1A1 P00352 1/20 0.47
DRD1 P21728 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3335710 1.00 FUCA1 (0.58) FUCA1GBA1SIGMAR1S1PR1S1PR5
SCHEMBL15477204 1.00 FUCA1 (0.58) FUCA1GBA1SIGMAR1S1PR1S1PR5
SCHEMBL5793338 1.00 FUCA1 (0.58) FUCA1GBA1SIGMAR1S1PR1S1PR5
Hydrochloric Acid SCHEMBL14780325 0.98 FUCA1 (0.56) FUCA1GBA1SIGMAR1S1PR1S1PR5
Hydrochloric Acid SCHEMBL14780326 0.98 FUCA1 (0.56) FUCA1GBA1SIGMAR1S1PR1S1PR5
SCHEMBL9180991 0.89 ALDH1A1 (0.53) GBA1SIGMAR1DRD2DRD3ALDH1A1
SCHEMBL25024428 0.86 FUCA1 (0.54) FUCA1GBA1SIGMAR1S1PR1S1PR5
SCHEMBL30233713 0.86 FUCA1 (0.54) FUCA1GBA1SIGMAR1S1PR1S1PR5
SCHEMBL16775256 0.84 FUCA1 (0.64) FUCA1GBA1SIGMAR1S1PR1S1PR5
SCHEMBL16759827 0.84 FUCA1 (0.64) FUCA1GBA1SIGMAR1S1PR1S1PR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250106-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-08-10 US disclosed
EP-3130592-B1 ANALOGUES OF 4H-PYRAZOLO[1,5- ]BENZIMIDAZOLE COMPOUND AS PARP INHIBITORS HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) 2019-08-14 EP disclosed
EP-3130592-B1 ANALOGUES OF 4H-PYRAZOLO[1,5- ]BENZIMIDAZOLE COMPOUND AS PARP INHIBITORS HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) 2019-08-14 EP disclosed
EP-3265459-B1 AMIDE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS SUVEN LIFE SCIENCES LTD (IN) 2019-05-15 EP disclosed
EP-2976337-B1 5-AMINO-QUINOLINE-8-CARBOXAMIDE DERIVATIVES AS 5-HT4 RECEPTOR AGONISTS SUVEN LIFE SCIENCES LTD (IN) 2018-05-02 EP disclosed
US-9957257-B2 Amide compounds as 5-HT4 receptor agonists SUVEN LIFE SCIENCES LIMITED (IN) 2018-05-01 US disclosed
US-9951045-B2 Indazole compounds as 5-HT4 receptor agonists SUVEN LIFE SCIENCES LIMITED (IN) 2018-04-24 US disclosed
US-20180051011-A1 AMIDE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS SUVEN LIFE SCIENCES LIMITED (IN) 2018-02-22 US disclosed
EP-3099675-B1 INDAZOLE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS SUVEN LIFE SCIENCES LTD (IN) 2018-02-14 EP disclosed
US-9856262-B2 Analogues of 4H-pyrazolo[1,5-a] benzimidazole compound as PARP inhibitors HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE INC. (CN) 2018-01-02 US disclosed
WO-2005026121-A1 PROCESS FOR THE PREPARATION OF (1α, 5α, 6α)-6-AMINOMETHYL-3-BENZYL-3-AZABICYCLO[3.1.0]HEXANE RANBAXY LABORATORIES LIMITED (IN) 2005-03-24 WO disclosed
WO-2004089364-A1 AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2004-10-21 WO disclosed
WO-2004089900-A1 AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2004-10-21 WO disclosed
EP-0413455-B1 Azabicyclo quinolone carboxylic acids PFIZER (US) 1995-06-21 EP disclosed
US-5391763-A 3-aza-bicyclo[3.1.0]hexanes which are intermediates for anti-bacterial azabicyclo quinolone carboxylic acids PFIZER INC. (US) 1995-02-21 US disclosed
US-5266569-A Azatricyclo carboxylic acids useful as anti-bacterial agents PFIZER INC. (US) 1993-11-30 US disclosed
US-5229396-A Anti-bacterial azabicyclo quinolone carboxylic acids PFIZER INC. (US) 1993-07-20 US disclosed
US-5164402-A Bactericides PFIZER INC (US) 1992-11-17 US disclosed
WO-1991002526-A1 AZABICYCLO QUINOLONE CARBOXYLIC ACIDS PFIZER INC. (US) 1991-03-07 WO disclosed
EP-0413455-A2 Azabicyclo quinolone carboxylic acids PFIZER INC. (US) 1991-02-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250106-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, CGAS, IRF3 FUCA1 2760/4885GBA1 209/4885SIGMAR1 3467/4885
US-20180051011-A1 AMIDE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS HTR4, HTR5A, HTR1A FUCA1 3598/4885GBA1 2554/4885SIGMAR1 159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.