Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10087500 | 0.97 | CXCR3 (0.97) | CXCR3 | |
| SCHEMBL5833010 | 0.94 | CXCR3 (1.00) | CXCR3 | |
| Hydrochloric Acid SCHEMBL5832526 | 0.93 | CXCR3 (1.00) | CXCR3 | |
| SCHEMBL5838280 | 0.91 | CXCR3 (1.00) | CXCR3 | |
| Hydrochloric Acid SCHEMBL5833406 | 0.91 | CXCR3 (0.99) | CXCR3 | |
| SCHEMBL27015149 | 0.83 | CXCR3 (0.87) | CXCR3 | |
| SCHEMBL3103733 | 0.83 | CXCR3 (0.84) | CXCR3 | |
| SCHEMBL13151350 | 0.83 | CXCR3 (0.84) | CXCR3 | |
| SCHEMBL13151360 | 0.82 | CXCR3 (0.86) | CXCR3 | |
| SCHEMBL13151357 | 0.81 | CXCR3 (0.83) | CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207170-B2 | Heterocyclic substituted piperazines with CXCR3 antagonist activity | SCHERING CORPORATION (US) | 2012-06-26 | — | — | US | disclosed |
| US-20120157466-A1 | HETEROCYCLIC COMPOUNDS WITH CXCR3 ANTAGONIST ACTIVITY | MERCK SHARP & DOHME CORP. | 2012-06-21 | — | — | US | disclosed |
| US-20110065651-A1 | HETEROCYCLIC SUBSTITUTED PIPERAZINES WITH CXCR3 ANTAGONIST ACTIVITY | SCHERING CORPORATION (US) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157466-A1 | HETEROCYCLIC COMPOUNDS WITH CXCR3 ANTAGONIST ACTIVITY | CXCR3, ACKR3, CXCR1 | CXCR3 1/4885 |
| US-20110065651-A1 | HETEROCYCLIC SUBSTITUTED PIPERAZINES WITH CXCR3 ANTAGONIST ACTIVITY | CXCR3, CXCR1, CCR5 | CXCR3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.