Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829473 | 0.99 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AHPGDTOP2A | |
| SCHEMBL23673315 | 0.95 | MAPT (0.51) | ALDH1A1MAPTKMT2AHPGDTOP2A | |
| SCHEMBL9831233 | 0.89 | MAPT (0.54) | ALDH1A1MAPTKMT2AHPGDTOP2A | |
| SCHEMBL25221002 | 0.86 | HPGD (0.58) | ALDH1A1MAPTKMT2AHPGDCYP1A2 | |
| SCHEMBL10108013 | 0.85 | ALDH1A1 (0.70) | ALDH1A1MAPTTOP2ACYP3A4CYP2C19 | |
| SCHEMBL5792896 | 0.84 | GAA (0.53) | ALDH1A1MAPTKMT2ATOP2AKYAT1 | |
| SCHEMBL8705157 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPTTOP2ACYP3A4CYP2C19 | |
| SCHEMBL11404787 | 0.84 | ALDH1A1 (0.68) | ALDH1A1MAPTTOP2ACYP3A4CYP2C19 | |
| SCHEMBL14570539 | 0.83 | TOP2A (0.53) | ALDH1A1MAPTTOP2ACYP1A2CYP3A4 | |
| SCHEMBL7712005 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2ATOP2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466161-B2 | Hydroxamate derivative, a production method for the same, and a pharmaceutical composition comprising the same | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-06-18 | — | — | US | disclosed |
| US-20120028963-A1 | NOVEL HYDROXAMATE DERIVATIVE, A PRODUCTION METHOD FOR THE SAME, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028963-A1 | NOVEL HYDROXAMATE DERIVATIVE, A PRODUCTION METHOD FOR THE SAME, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HAAO, HPD, HCAR2 | ALDH1A1 910/4885MAPT 1675/4885KMT2A 1000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.