Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986300 | 0.81 | AKR1C3 (0.38) | NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL441499 | 0.81 | NPC1 (0.32) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13328292 | 0.77 | ALDH1A1 (0.47) | NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL13592741 | 0.73 | LMNA (0.34) | NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14282584 | 0.73 | AKR1C3 (0.44) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8986294 | 0.73 | GCGR (0.36) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13593066 | 0.70 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8986306 | 0.69 | AKR1C3 (0.40) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8986301 | 0.67 | AKR1C3 (0.38) | NPC1RAB9A | |
| SCHEMBL13638717 | 0.67 | AKR1C3 (0.38) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445695-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-05-21 | — | — | US | disclosed |
| US-8278439-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-10-02 | — | — | US | disclosed |
| US-20120065391-A1 | SYNTHESIS OF PHOSPHONO-SUBSTITUTED PORPHYRIN COMPOUNDS FOR ATTACHMENT TO METAL OXIDE SURFACES | LINDSEY JONATHAN S (US) | 2012-03-15 | — | — | US | disclosed |
| US-8080653-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-12-20 | — | — | US | disclosed |
| US-20090234136-A1 | SYNTHESIS OF PHOSPHONO-SUBSTITUTED PORPHYRIN COMPOUNDS FOR ATTACHMENT TO METAL OXIDE SURFACES | LINDSEY JONATHAN S | 2009-09-17 | — | — | US | disclosed |
| US-7314941-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-01-01 | — | — | US | disclosed |
| US-20070055060-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | LINDSEY JONATHAN S | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234136-A1 | SYNTHESIS OF PHOSPHONO-SUBSTITUTED PORPHYRIN COMPOUNDS FOR ATTACHMENT TO METAL OXIDE SURFACES | PPOX, DAO, DDO | NPC1 4865/4885RAB9A 3987/4885SMN1; SMN2 4841/4885 |
| US-20070055060-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | PPOX, DAO, DDO | NPC1 4865/4885RAB9A 3987/4885SMN1; SMN2 4841/4885 |
| US-20120065391-A1 | SYNTHESIS OF PHOSPHONO-SUBSTITUTED PORPHYRIN COMPOUNDS FOR ATTACHMENT TO METAL OXIDE SURFACES | PPOX, DAO, DDO | NPC1 4865/4885RAB9A 3987/4885SMN1; SMN2 4841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.