Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 3/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986320 | 0.82 | MAPT (0.36) | GCGRLMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL11921695 | 0.80 | MAPT (0.34) | GCGRLMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL8986337 | 0.80 | MAPT (0.34) | GCGRLMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL11920183 | 0.79 | GCGR (0.34) | GCGRLMNAALDH1A1GAARAB9A | |
| SCHEMBL8986351 | 0.78 | BCHE (0.35) | GCGRLMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11920182 | 0.76 | BCHE (0.33) | GCGRRAB9ANPC1SRD5A2BCHE | |
| SCHEMBL8986300 | 0.76 | AKR1C3 (0.38) | LMNAALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL19622539 | 0.74 | L3MBTL1 (0.41) | LMNAALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8986298 | 0.74 | TSHR (0.35) | LMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL10108773 | 0.73 | NPC1 (0.31) | RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304561-B2 | Synthetic route to ABCD-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-11-06 | — | — | US | disclosed |
| US-8304561-B2 | Synthetic route to ABCD-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-11-06 | — | — | US | disclosed |
| US-20120209009-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-08-16 | — | — | US | disclosed |
| US-20120209009-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-08-16 | — | — | US | disclosed |
| US-8188298-B2 | Synthetic route to ABCD-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188298-B2 | Synthetic route to ABCD-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-05-29 | — | — | US | disclosed |
| US-20110306774-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-12-15 | — | — | US | disclosed |
| US-20110306774-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-12-15 | — | — | US | disclosed |
| US-7994312-B2 | Synthetic route to ABCD-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-08-09 | — | — | US | disclosed |
| US-7994312-B2 | Synthetic route to ABCD-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-08-09 | — | — | US | disclosed |
| US-20090082576-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-03-26 | — | — | US | disclosed |
| US-20090082576-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-03-26 | — | — | US | disclosed |
| WO-2008100461-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120209009-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | ABCB7, ALAD, SLC39A14 | GCGR 4832/4885LMNA 4635/4885ALDH1A1 1829/4885 |
| US-20090082576-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | ABCB7, ALAD, SLC39A14 | GCGR 4832/4885LMNA 4635/4885ALDH1A1 1829/4885 |
| US-20110306774-A1 | SYNTHETIC ROUTE TO ABCD-PORPHYRINS | ABCB7, ALAD, SLC39A14 | GCGR 4832/4885LMNA 4635/4885ALDH1A1 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.