Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | DCAF15 | Q66K64 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2514598 | 0.77 | CYP1A2 (0.63) | CYP1A2CYP2D6HTR1DTAAR1LMNA | |
| SCHEMBL28089668 | 0.74 | CYP1A2 (0.58) | CYP1A2CYP2D6HTR1DHTR1BALDH1A1 | |
| SCHEMBL27326985 | 0.74 | CYP1A2 (0.58) | CYP1A2CYP2D6HTR1DHTR1BALDH1A1 | |
| SCHEMBL6185754 | 0.72 | CYP1A2 (0.57) | CYP1A2CYP2D6HTR1DHTR1BTAAR1 | |
| SCHEMBL11135471 | 0.72 | CYP1A2 (0.71) | CYP1A2CYP2D6HTR1DHTR1BTAAR1 | |
| SCHEMBL27666013 | 0.71 | CYP1A2 (0.51) | CYP1A2CYP2D6 | |
| SCHEMBL11190216 | 0.71 | CYP2D6 (0.51) | CYP1A2CYP2D6HTR1DHTR1BALDH1A1 | |
| SCHEMBL13990186 | 0.70 | CYP1A2 (1.00) | CYP1A2CYP2D6HTR1DHTR1BDRD4 | |
| SCHEMBL10608056 | 0.70 | CYP1A2 (0.54) | CYP1A2CYP2D6HTR1DHTR1BALDH1A1 | |
| SCHEMBL23121057 | 0.70 | CYP1A2 (0.70) | CYP1A2CYP2D6HTR1DHTR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11185853-B2 | Catalysts for polycarbonate production | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2021-11-30 | — | — | US | disclosed |
| US-10662211-B2 | Catalysts and methods for polymer synthesis | Saurdi Aramco Technologies Company (SA) | 2020-05-26 | — | — | US | disclosed |
| US-10464960-B2 | Salen complexes with dianionic counterions | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2019-11-05 | — | — | US | disclosed |
| US-20190193062-A1 | CATALYSTS FOR POLYCARBONATE PRODUCTION | ARAMCO PERFORMANCE MATERIALS LLC | 2019-06-27 | — | — | US | disclosed |
| US-20180179242-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. | 2018-06-28 | — | — | US | disclosed |
| US-20180179242-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. | 2018-06-28 | — | — | US | disclosed |
| US-9951096-B2 | Catalysts and methods for polymer synthesis | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2018-04-24 | — | — | US | disclosed |
| US-9951096-B2 | Catalysts and methods for polymer synthesis | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2018-04-24 | — | — | US | disclosed |
| US-9856349-B2 | Catalysts and methods for polymer synthesis | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2018-01-02 | — | — | US | disclosed |
| US-20170183369-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-06-29 | — | — | US | disclosed |
| US-8946109-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140336354-A1 | SALEN COMPLEXES WITH DIANIONIC COUNTERIONS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2014-11-13 | — | — | US | disclosed |
| US-20130172524-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130144031-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130144032-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130144033-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-06-06 | — | — | US | disclosed |
| US-8101782-B2 | Drug hybrid of rivastigmine or physostigmine with tranylcypromine, amoxapine, desipramine, nortriptyline, protriptyline, fluoxetine, fluvoxamine, paroxetine, duloxetine, betahistine, amlodipine, proylhexedrine, rimantadine, desloratadine; Alzheimer's disease; Parkinson's disease, impairment in memory | COLUCID PHARMACEUTICALS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-8101782-B2 | Drug hybrid of rivastigmine or physostigmine with tranylcypromine, amoxapine, desipramine, nortriptyline, protriptyline, fluoxetine, fluvoxamine, paroxetine, duloxetine, betahistine, amlodipine, proylhexedrine, rimantadine, desloratadine; Alzheimer's disease; Parkinson's disease, impairment in memory | COLUCID PHARMACEUTICALS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-20080261950-A1 | Compounds that inhibit cholinesterase | COLUCID PHARMACEUTICALS, INC. (US) | 2008-10-23 | — | — | US | disclosed |
| US-20080261950-A1 | Compounds that inhibit cholinesterase | COLUCID PHARMACEUTICALS, INC. (US) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662211-B2 | Catalysts and methods for polymer synthesis | PPOX, COASY, SOD1 | CYP1A2 501/4885CYP2D6 690/4885HTR1D 4882/4885 |
| US-10464960-B2 | Salen complexes with dianionic counterions | NCLN, POLN, NCL | CYP1A2 4812/4885CYP2D6 3658/4885HTR1D 4878/4885 |
| US-20140336354-A1 | SALEN COMPLEXES WITH DIANIONIC COUNTERIONS | NCLN, POLN, NCL | CYP1A2 4812/4885CYP2D6 3658/4885HTR1D 4878/4885 |
| US-20130144032-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | CYP1A2 501/4885CYP2D6 690/4885HTR1D 4882/4885 |
| US-20180179242-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | CYP1A2 501/4885CYP2D6 690/4885HTR1D 4882/4885 |
| US-20130144033-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | CYP1A2 501/4885CYP2D6 690/4885HTR1D 4882/4885 |
| US-20080261950-A1 | Compounds that inhibit cholinesterase | ACHE, BCHE, CHAT | CYP1A2 537/4885CYP2D6 956/4885HTR1D 1726/4885 |
| US-20170183369-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | CYP1A2 501/4885CYP2D6 690/4885HTR1D 4882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.