SCHEMBL10108865

SCHEMBL10108865

COC(=O)c1ccccc1-c1cccc2c1sc1ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 1/20 0.59
LMNA P02545 2/20 0.49
MAPK1 P28482 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.48
ATM Q13315 3/20 0.48
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 3/20 0.48
MEN1 O00255 2/20 0.48
MAPT P10636 2/20 0.48
KMT2A Q03164 2/20 0.48
HSD17B10 Q99714 2/20 0.48
GLA P06280 1/20 0.48
GAA P10253 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX5 P09917 1/20 0.46
SLC6A3 Q01959 4/20 0.46
SLC6A4 P31645 3/20 0.46
SLC6A2 P23975 1/20 0.43
TSHR P16473 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24068240 0.88 LMNA (0.54) PARP14LMNAMAPK1L3MBTL1ATM
SCHEMBL4554303 0.87 PARP14 (0.52) PARP14LMNAMAPK1L3MBTL1ATM
SCHEMBL16162945 0.86 PARP14 (0.51) PARP14LMNAMAPK1L3MBTL1ATM
SCHEMBL17126826 0.86 PARP14 (0.51) PARP14LMNAMAPK1L3MBTL1ATM
SCHEMBL18539206 0.81 SLC6A3 (0.59) LMNAATMALDH1A1KDM4EMEN1
SCHEMBL18647347 0.81 PARP14 (0.56) PARP14ALDH1A1KDM4EMAPTHSD17B10
SCHEMBL18566659 0.79 PARP14 (0.44) PARP14LMNAMAPK1L3MBTL1ATM
SCHEMBL14943815 0.78 LMNA (0.50) LMNAMAPK1L3MBTL1ATMALDH1A1
SCHEMBL19879994 0.78 LMNA (0.42) PARP14LMNAMAPK1L3MBTL1ATM
SCHEMBL22870943 0.78 SLC6A3 (0.46) PARP14LMNAMAPK1L3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4063466-A1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING SAME Samsung SDI Co., Ltd. (KR) 2022-09-28 EP disclosed
US-11145820-B2 Organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2021-10-12 US disclosed
US-10333081-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode SAMSUNG SDI CO., LTD. (KR) 2019-06-25 US disclosed
EP-2940097-B1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING SAME CHEIL IND INC (KR) 2019-03-20 EP disclosed
US-20180138423-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE SAMSUNG SDI CO LTD (KR) 2018-05-17 US disclosed
US-20180138423-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE SAMSUNG SDI CO LTD (KR) 2018-05-17 US disclosed
US-9899607-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode SAMSUNG SDI CO., LTD. (KR) 2018-02-20 US disclosed
US-9899607-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode SAMSUNG SDI CO., LTD. (KR) 2018-02-20 US disclosed
EP-3243888-A1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING SAME Cheil Industries Inc. (KR) 2017-11-15 EP disclosed
US-9755157-B2 Organic compound and organic optoelectric device and display device CHEIL INDUSTRIES, INC. (KR) 2017-09-05 US disclosed
US-20150280136-A1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-10-01 US disclosed
US-20150280136-A1 ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-10-01 US disclosed
EP-2889296-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING SAME, AND DISPLAY DEVICE INCLUDING ORGANIC LIGHT-EMITTING DIODE Cheil Industries Inc. (KR) 2015-07-01 EP disclosed
US-20150144938-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE SAMSUNG SDI CO., LTD. (KR) 2015-05-28 US disclosed
US-20150144938-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE SAMSUNG SDI CO., LTD. (KR) 2015-05-28 US disclosed
US-20150034914-A1 ORGANIC COMPOUND AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE CHEIL INDUSTRIES, INC. (KR) 2015-02-05 US disclosed
US-20150034914-A1 ORGANIC COMPOUND AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE CHEIL INDUSTRIES, INC. (KR) 2015-02-05 US disclosed
EP-2450975-B1 Compound for organic optoelectronic device and organic light emitting diode including the same CHEIL IND INC (KR) 2014-01-08 EP disclosed
US-20120112174-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-05-10 US disclosed
US-20120112174-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120112174-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE AOX1, OCIAD1, OCIAD2 PARP14 4799/4885LMNA 4819/4885MAPK1 486/4885
US-20180138423-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE OR51E2, AOX1, ODC1 PARP14 4602/4885LMNA 3975/4885MAPK1 981/4885
US-20150144938-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE OR51E2, AOX1, ODC1 PARP14 4602/4885LMNA 3975/4885MAPK1 981/4885
US-11145820-B2 Organic optoelectronic device and display device OCIAD2, OCIAD1, AOX1 PARP14 3999/4885LMNA 4489/4885MAPK1 301/4885
US-10333081-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode OR51E2, AOX1, ODC1 PARP14 4602/4885LMNA 3975/4885MAPK1 981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.