Sugi Predict

Sugi Predict / Compounds / SCHEMBL18647347

SCHEMBL18647347

SCHEMBL18647347

NC(=O)c1ccccc1-c1cccc2c1sc1ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PARP14 Q460N5 1/20 0.56
▸ ALOX5 P09917 1/20 0.49
▸ BCAT2 O15382 1/20 0.46
▸ LIMK1 P53667 2/20 0.45
▸ IKBKB O14920 1/20 0.45
▸ KDM4E B2RXH2 4/20 0.43
▸ NUDT1 P36639 1/20 0.43
▸ KEAP1 Q14145 1/20 0.41
▸ NFE2L2 Q16236 1/20 0.41
▸ PRKDC P78527 3/20 0.41
▸ ALDH1A1 P00352 3/20 0.40
▸ GLA P06280 1/20 0.40
▸ GPR3 P46089 1/20 0.39
▸ PIK3CD O00329 2/20 0.39
▸ PIK3CB P42338 2/20 0.39
▸ BRD4 O60885 1/20 0.39
▸ PIK3CA P42336 1/20 0.39
▸ MTOR P42345 1/20 0.39
▸ PIK3CG P48736 1/20 0.39
▸ KCNH2 Q12809 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18646818 0.88 PARP14 (0.44) PARP14ALOX5BCAT2LIMK1IKBKB
SCHEMBL17395373 0.87 LIMK1 (0.50) PARP14ALOX5LIMK1IKBKBKDM4E
SCHEMBL18647390 0.81 BCAT2 (0.46) PARP14BCAT2LIMK1IKBKBKDM4E
SCHEMBL16553319 0.81 ALOX5 (0.61) PARP14ALOX5LIMK1PRKDCALDH1A1
SCHEMBL10108865 0.81 PARP14 (0.59) PARP14ALOX5KDM4EALDH1A1GLA
SCHEMBL10018846 0.79 ALOX5 (0.59) PARP14ALOX5LIMK1PRKDCALDH1A1
SCHEMBL431845 0.79 ALOX5 (0.59) PARP14ALOX5LIMK1PRKDCALDH1A1
SCHEMBL429382 0.79 ALOX5 (0.59) PARP14ALOX5LIMK1PRKDCALDH1A1
SCHEMBL12996528 0.79 ALOX5 (0.59) PARP14ALOX5LIMK1PRKDCALDH1A1
SCHEMBL30646218 0.79 BCAT2 (0.63) BCAT2KDM4ENUDT1KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10968208-B2 Compound for organic electronic element, organic electronic element comprising the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2021-04-06 — — US disclosed
US-20200223835-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2020-07-16 — — US disclosed
WO-2017043797-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2017-03-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10968208-B2 Compound for organic electronic element, organic electronic element comprising the same, and electronic device thereof PIEZO1, OCIAD1, EML4 PARP14 3367/4885ALOX5 1530/4885BCAT2 2793/4885
US-20200223835-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, EML4 PARP14 3367/4885ALOX5 1530/4885BCAT2 2793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.