Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102870 | 0.87 | ALDH1A1 (0.41) | KMT2ATDP1HTTNAMPTALDH1A1 | |
| SCHEMBL16219492 | 0.79 | KMT2A (0.44) | KMT2ATDP1HTTPOLBMEN1 | |
| SCHEMBL16219381 | 0.79 | KMT2A (0.44) | KMT2ATDP1HTTNAMPTPOLB | |
| SCHEMBL12139785 | 0.76 | KMT2A (0.47) | KMT2ATDP1HTTPOLBNPSR1 | |
| SCHEMBL13347327 | 0.75 | KMT2A (0.73) | KMT2ATDP1HTTPOLBMEN1 | |
| SCHEMBL10245087 | 0.74 | TDP1 (0.54) | KMT2AEPHX1TDP1HTTNAMPT | |
| SCHEMBL18713107 | 0.72 | KDM4E (0.46) | KMT2ATDP1HTTALDH1A1HPGD | |
| SCHEMBL16219382 | 0.69 | KMT2A (0.47) | KMT2ATDP1HTTPOLBNPSR1 | |
| SCHEMBL16219489 | 0.69 | RBP4 (0.52) | KMT2ATDP1HTTALDH1A1POLB | |
| SCHEMBL16103859 | 0.68 | KMT2A (0.60) | KMT2ATDP1HTTNAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015959-A1 | HETEROCYCLIC COMPOUNDS AS AUTOTAXIN INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015959-A1 | HETEROCYCLIC COMPOUNDS AS AUTOTAXIN INHIBITORS | ENPP2, HAX1, MTX1 | KMT2A 1968/4885EPHX1 171/4885TDP1 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.