Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203923 | 0.75 | AKT1 (0.33) | KDM4EHPGDMAPTL3MBTL1GAA | |
| SCHEMBL28341512 | 0.74 | MPO (0.33) | KDM4EMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL6229399 | 0.73 | HTT (0.45) | KDM4EHPGDMAPTL3MBTL1MEN1 | |
| SCHEMBL13817406 | 0.72 | KDM4E (0.46) | KDM4EHPGDMAPTL3MBTL1MEN1 | |
| SCHEMBL25002441 | 0.72 | AR (0.48) | KDM4EHPGDMAPTL3MBTL1GAA | |
| SCHEMBL21008390 | 0.72 | AR (0.48) | KDM4EHPGDMAPTL3MBTL1GAA | |
| SCHEMBL21677885 | 0.71 | MAPT (0.40) | KDM4EHPGDMAPTL3MBTL1MEN1 | |
| SCHEMBL6229314 | 0.70 | POLB (0.48) | KDM4EHPGDMAPTL3MBTL1MEN1 | |
| SCHEMBL10109755 | 0.70 | ADORA2A (0.40) | MEN1KMT2AGAAPKMSRC | |
| SCHEMBL11985476 | 0.70 | ALDH1A1 (0.46) | KDM4EHPGDMAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10840397-B2 | Highly-fluorescent and photo-stable chromophores for wavelength conversion | NITTO DENKO CORPORATION (JP) | 2020-11-17 | — | — | US | disclosed |
| US-10461201-B2 | Highly-fluorescent and photo-stable chromophores for wavelength conversion | NITTO DENKO CORPORATION (JP) | 2019-10-29 | — | — | US | disclosed |
| US-9960294-B2 | Highly fluorescent and photo-stable chromophores for wavelength conversion | NITTO DENKO CORPORATION (JP) | 2018-05-01 | — | — | US | disclosed |
| US-9960294-B2 | Highly fluorescent and photo-stable chromophores for wavelength conversion | NITTO DENKO CORPORATION (JP) | 2018-05-01 | — | — | US | disclosed |
| EP-2941474-B1 | HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION | NITTO DENKO CORP (JP) | 2018-02-28 | — | — | EP | disclosed |
| US-9682998-B2 | Fused heterocyclic compounds as ion channel modulators | GILEAD SCIENCES, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-9682998-B2 | Fused heterocyclic compounds as ion channel modulators | GILEAD SCIENCES, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160362421-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES, INC. | 2016-12-15 | — | — | US | disclosed |
| US-9403782-B2 | Fused heterocyclic compounds as ion channel modulators | GILEAD SCIENCES, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-20150340519-A1 | HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION | NITTO DENKO CORPORATION (JP) | 2015-11-26 | — | — | US | disclosed |
| US-20150340519-A1 | HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION | NITTO DENKO CORPORATION (JP) | 2015-11-26 | — | — | US | disclosed |
| US-20150329558-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES, INC. | 2015-11-19 | — | — | US | disclosed |
| WO-2015168439-A1 | INORGANIC OXIDE COATED FLUORESCENT CHROMOPHORES FOR USE IN HIGHLY PHOTOSTABLE WAVELENGTH CONVERSION FILMS | NITTO DENKO CORPORATION (JP) | 2015-11-05 | — | — | WO | disclosed |
| US-9115096-B2 | Fused heterocyclic compounds as ion channel modulators | GILEAD SCIENCES, INC. (US) | 2015-08-25 | — | — | US | disclosed |
| WO-2014197393-A1 | PHOTOSTABLE WAVELENGTH CONVERSION COMPOSITION | NITTO DENKO CORPORATION (JP) | 2014-12-11 | — | — | WO | disclosed |
| WO-2014107606-A2 | HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION | NITTO DENKO CORPORATION (JP) | 2014-07-10 | — | — | WO | disclosed |
| US-20120289493-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES, INC. | 2012-11-15 | — | — | US | disclosed |
| US-20120289493-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES, INC. | 2012-11-15 | — | — | US | disclosed |
| US-20120053181-A1 | PYRROLIDINE-DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME, CORP. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120053181-A1 | PYRROLIDINE-DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME, CORP. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053181-A1 | PYRROLIDINE-DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | ADRB3, ADRB1, ADRB2 | KDM4E 3792/4885HPGD 684/4885MAPT 2633/4885 |
| US-20120289493-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | KCNJ2, CACNA1A, KCNH2 | KDM4E 1666/4885HPGD 1186/4885MAPT 4552/4885 |
| US-20160362421-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | KCNJ2, CACNA1A, KCNH2 | KDM4E 1666/4885HPGD 1186/4885MAPT 4552/4885 |
| US-20150329558-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | KCNJ2, CACNA1A, KCNH2 | KDM4E 1666/4885HPGD 1186/4885MAPT 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.