SCHEMBL1011201

SCHEMBL1011201

CCCCc1ncn(CCC(F)(F)F)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25860658 0.83 CXCR3 (0.32)
SCHEMBL1229601 0.78 KDR (0.40)
SCHEMBL22366300 0.77 CXCR3 (0.31)
SCHEMBL27573009 0.77 KDR (0.42)
SCHEMBL1011560 0.76 KDR (0.36)
SCHEMBL1011975 0.76 KDR (0.36)
SCHEMBL23989423 0.73
SCHEMBL21634179 0.73 LMNA (0.34)
SCHEMBL9036100 0.71 KDR (0.38)
SCHEMBL9274617 0.71 KCNH2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1960345-B1 ALKYLATION OF N' -PHENYL-N-ALKYLPHENYLENEDIAMINES IN IONIC LIQUID, AND N' -PHENYL-N-ALKYL(ALKYLPHENYLENE) DIAMINES PRODUCED THEREBY CHEMTURA CORP (US) 2014-11-19 EP claimed
EP-1963253-B1 RING ALKYLATION OF ANILINE OR AN ANILINE DERIVATIVE USING IONIC LIQUID CATALYSTS CHEMTURA CORP (US) 2011-01-05 EP claimed
EP-1960344-B1 ALKYLATION OF A DIPHENYLAMINE COMPOUND IN IONIC LIQUID CHEMTURA CORP (US) 2010-09-29 EP claimed
US-7563929-B2 Alkylation of N′-phenyl-N-alkylphenylenediamines in ionic liquid and N′-phenyl-N-alkyl(alkylphenylene) diamines produced thereby CHEMTURA CORPORATION (US) 2009-07-21 US claimed
US-20080234517-A1 ALKYLATION OF N'-PHENYL-N-ALKYLPHENYLENEDIAMINES IN IONIC LIQUID AND N'-PHENYL-N-ALKYL(ALKYLPHENYLENE) DIAMINES PRODUCED THEREBY CHEMTURA CORPORATION (US) 2008-09-25 US claimed
EP-1963253-A2 RING ALKYLATION OF ANILINE OR AN ANILINE DERIVATIVE USING IONIC LIQUID CATALYSTS CHEMTURA CORPORATION (US) 2008-09-03 EP claimed
US-7378554-B2 Ring alkylation of aniline or an aniline derivative using ionic liquid catalysts CHEMTURA CORPORATION (US) 2008-05-27 US claimed
WO-2007070263-A2 RING ALKYLATION OF ANILINE OR AN ANILINE DERIVATIVE USING IONIC LIQUID CATALYSTS CHEMTURA CORPORATION (US) 2007-06-21 WO claimed
US-20070135656-A1 Ring alkylation of aniline or an aniline derivative using ionic liquid catalysts LANXESS SOLUTIONS US INC. 2007-06-14 US claimed
US-20070135657-A1 Alkylation of N'-phenyl-N-alkylphenylenediamines in ionic liquid, N'-phenyl-N-alkyl (alkylphenylene) diamines produced thereby, and lubricant compositions containing same LANXESS SOLUTIONS US INC. 2007-06-14 US claimed
US-7145038-B1 Alkylation of a diphenylamine compound in ionic liquid CHEMTURA CORPORATION (US) 2006-12-05 US claimed
EP-1960345-B1 ALKYLATION OF N' -PHENYL-N-ALKYLPHENYLENEDIAMINES IN IONIC LIQUID, AND N' -PHENYL-N-ALKYL(ALKYLPHENYLENE) DIAMINES PRODUCED THEREBY CHEMTURA CORP (US) 2014-11-19 EP disclosed
EP-1963253-B1 RING ALKYLATION OF ANILINE OR AN ANILINE DERIVATIVE USING IONIC LIQUID CATALYSTS CHEMTURA CORP (US) 2011-01-05 EP disclosed
EP-1960344-B1 ALKYLATION OF A DIPHENYLAMINE COMPOUND IN IONIC LIQUID CHEMTURA CORP (US) 2010-09-29 EP disclosed
US-7563929-B2 Alkylation of N′-phenyl-N-alkylphenylenediamines in ionic liquid and N′-phenyl-N-alkyl(alkylphenylene) diamines produced thereby CHEMTURA CORPORATION (US) 2009-07-21 US disclosed
US-7390928-B2 Alkylation of N′-phenyl-N-alkylphenylenediamines in ionic liquid, N′-phenyl-N-alkyl (alkylphenylene) diamines produced thereby, and lubricant compositions containing same CHEMTURA CORPORATION (US) 2008-06-24 US disclosed
US-7378554-B2 Ring alkylation of aniline or an aniline derivative using ionic liquid catalysts CHEMTURA CORPORATION (US) 2008-05-27 US disclosed
US-20070135656-A1 Ring alkylation of aniline or an aniline derivative using ionic liquid catalysts LANXESS SOLUTIONS US INC. 2007-06-14 US disclosed
US-20070135657-A1 Alkylation of N'-phenyl-N-alkylphenylenediamines in ionic liquid, N'-phenyl-N-alkyl (alkylphenylene) diamines produced thereby, and lubricant compositions containing same LANXESS SOLUTIONS US INC. 2007-06-14 US disclosed
US-7145038-B1 Alkylation of a diphenylamine compound in ionic liquid CHEMTURA CORPORATION (US) 2006-12-05 US disclosed