Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10112898 | 0.84 | TLR8 (0.46) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL10112906 | 0.82 | ALOX5AP (0.46) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL10112886 | 0.77 | TLR8 (0.49) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL10112950 | 0.77 | TLR8 (0.49) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL12780756 | 0.76 | TLR8 (0.67) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL12122765 | 0.75 | TLR8 (0.58) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL22169507 | 0.74 | HSD11B1 (0.57) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL6177743 | 0.74 | TLR8 (0.56) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL12433514 | 0.73 | MAPT (0.50) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL11508991 | 0.72 | TLR8 (0.52) | TLR8MAPTHSD11B1BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120052412-A1 | POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF | HONDA MOTOR CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |