Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 15/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10112892 | 0.82 | TLR8 (0.47) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL10112898 | 0.79 | TLR8 (0.46) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL10129669 | 0.79 | ALOX5AP (0.33) | ALOX5APHSD11B1 | |
| SCHEMBL12122765 | 0.73 | TLR8 (0.58) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL10112886 | 0.72 | TLR8 (0.49) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL10112950 | 0.72 | TLR8 (0.49) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL12780756 | 0.72 | TLR8 (0.67) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL12433514 | 0.72 | MAPT (0.50) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL10112879 | 0.70 | ESR1 (0.45) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL22169507 | 0.70 | HSD11B1 (0.57) | TLR8MAPTHSD11B1BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120052412-A1 | POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF | HONDA MOTOR CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |