Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10112886 | 1.00 | TLR8 (0.49) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL12780756 | 0.78 | TLR8 (0.67) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL9846977 | 0.78 | POLB (0.56) | ALDH1A1L3MBTL1EZH2ESR1ESR2 | |
| SCHEMBL13910344 | 0.77 | GAA (0.41) | TLR8MAPTALDH1A1KDM4EAR | |
| SCHEMBL12122765 | 0.77 | TLR8 (0.58) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL10112892 | 0.77 | TLR8 (0.47) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL10112879 | 0.77 | ESR1 (0.45) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL10129305 | 0.76 | ADORA3 (0.36) | TLR8MAPTHSD11B1 | |
| SCHEMBL10112898 | 0.76 | TLR8 (0.46) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL22169507 | 0.76 | HSD11B1 (0.57) | TLR8MAPTHSD11B1BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120052412-A1 | POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF | HONDA MOTOR CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |