Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 12/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10112892 | 0.84 | TLR8 (0.47) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL10112906 | 0.79 | ALOX5AP (0.46) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL10112950 | 0.76 | TLR8 (0.49) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL10112886 | 0.76 | TLR8 (0.49) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL10112879 | 0.76 | ESR1 (0.45) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL12780756 | 0.75 | TLR8 (0.67) | TLR8MAPTHSD11B1EZH2BCL2L1 | |
| SCHEMBL12122765 | 0.74 | TLR8 (0.58) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL2710488 | 0.74 | GRIN2D (0.48) | PGRESR1MEN1LMNAHTT | |
| SCHEMBL6177743 | 0.73 | TLR8 (0.56) | TLR8MAPTHSD11B1BCL2L1MCL1 | |
| SCHEMBL22169507 | 0.73 | HSD11B1 (0.57) | TLR8MAPTHSD11B1BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120052412-A1 | POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF | HONDA MOTOR CO., LTD. (JP) | 2012-03-01 | — | — | US | disclosed |