SCHEMBL101143

SCHEMBL101143

OCC(O)COCCCOCC(O)CO

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.68
HTT P42858 1/20 0.43
LMNA P02545 4/20 0.42
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.39
PLA2G2C Q5R387 1/20 0.38
LPAR5 Q9H1C0 1/20 0.37
CYP1A2 P05177 2/20 0.36
AGTR1 P30556 1/20 0.36
KDM4E B2RXH2 2/20 0.35
DUSP3 P51452 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
THRB P10828 1/20 0.35
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9422103 0.97 USP2 (0.65) USP2HTTLMNAALDH1A1HSD17B10
SCHEMBL11042040 0.94 USP2 (0.75) USP2HTTLMNAALDH1A1HSD17B10
SCHEMBL8622815 0.92 USP2 (0.79) USP2HTTLMNAALDH1A1HSD17B10
SCHEMBL29837928 0.92 USP2 (0.79) USP2HTTLMNAALDH1A1HSD17B10
SCHEMBL8620507 0.92 USP2 (0.79) USP2HTTLMNAALDH1A1HSD17B10
SCHEMBL6230528 0.92 USP2 (0.79) USP2HTTLMNAALDH1A1HSD17B10
SCHEMBL8622282 0.92 USP2 (0.79) USP2HTTLMNAALDH1A1HSD17B10
SCHEMBL8619644 0.92 USP2 (0.79) USP2HTTLMNAALDH1A1HSD17B10
SCHEMBL3108971 0.92 USP2 (0.72) USP2HTTLMNAALDH1A1HSD17B10
SCHEMBL58458 0.90 USP2 (0.63) USP2HTTLMNAALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230243837-A1 Novel Reagents for Directed Biomarker Signal Amplification SIRIGEN, INC. 2023-08-03 US disclosed
US-20170307990-A1 IMAGE BEARING MEMBER FOR ELECTROPHOTOGRAPHY AND METHOD FOR PRODUCING THE SAME Konica Minolta, Inc. (JP) 2017-10-26 US disclosed
US-8865944-B2 Process for the purification of polyol PFPE derivatives SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2014-10-21 US disclosed
US-8664353-B2 Process for the purification of polyol PFPE derivatives SOLVAY SOLEXIS S.P.A. (IT) 2014-03-04 US disclosed
US-8513471-B2 Process for the manufacture of polyol perfluoropolyether derivative SOLVAY SOLEXIS S.P.A. (IT) 2013-08-20 US disclosed
US-8304515-B2 Process for the purification of polyol PFPE derivative SOLVAY SOLEXIS S.P.A. (IT) 2012-11-06 US disclosed
US-20120055779-A1 Process for the purification of polyol PFPE derivatives SOLVAY SOLEXIS S.P.A. (IT) 2012-03-08 US disclosed
US-20120059144-A1 Process for the purification of polyol PFPE derivatives SOLVAY SOLEXIS S.P.A. (IT) 2012-03-08 US disclosed
US-8017807-B2 Tetrahydroxy compound, method for preparing the tetrahydroxy compound, and photoreceptor using the tetrahydroxy compound RICOH COMPANY LIMITED (JP) 2011-09-13 US disclosed
US-20110003968-A1 Process for the purification of polyol PFPE derivative SOLVAY SOLEXIS S.P.A. (IT) 2011-01-06 US disclosed
US-20100240930-A1 Process for the manufacture of polyol perfluoropolyether derivative SOLVAY SOLEXIS S.P.A. (IT) 2010-09-23 US disclosed
US-20070128530-A1 TETRAHYDROXY COMPOUND, METHOD FOR PREPARING THE TETRAHYDROXY COMPOUND, AND PHOTORECEPTOR USING THE TETRAHYDROXY COMPOUND RICOH COMPANY, LTD. (JP) 2007-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230243837-A1 Novel Reagents for Directed Biomarker Signal Amplification RNGTT, CAPG, CD2BP2 USP2 1631/4885HTT 4444/4885LMNA 1915/4885
US-20100240930-A1 Process for the manufacture of polyol perfluoropolyether derivative AFF2, AFF1, AFF4 USP2 1149/4885HTT 2711/4885LMNA 2161/4885
US-20120059144-A1 Process for the purification of polyol PFPE derivatives PHYKPL, PKLR, PHOSPHO1 USP2 440/4885HTT 2184/4885LMNA 2429/4885
US-20070128530-A1 TETRAHYDROXY COMPOUND, METHOD FOR PREPARING THE TETRAHYDROXY COMPOUND, AND PHOTORECEPTOR USING THE TETRAHYDROXY COMPOUND ALDH1A2, SLC9B2, SLC18A2 USP2 4603/4885HTT 2040/4885LMNA 3075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.