SCHEMBL10114795

SCHEMBL10114795

COCc1cc(C(C)(C)C)cc(CCO)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 5/20 0.46
PRKCE Q02156 3/20 0.40
MYLK Q15746 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MEN1 O00255 1/20 0.40
PRKCG P05129 1/20 0.40
MAPT P10636 1/20 0.40
PRKCA P17252 1/20 0.40
APEX1 P27695 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
CYP2D6 P10635 5/20 0.37
CYP2C9 P11712 4/20 0.37
CYP1A2 P05177 3/20 0.37
HIF1A Q16665 2/20 0.37
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12151245 0.90 PRKCE (0.40) CYP2C19PRKCEMYLKALDH1A1MEN1
SCHEMBL16850512 0.90 ALOX15 (0.46) CYP2C19PRKCEMYLKALDH1A1MEN1
SCHEMBL10114799 0.90 PRKCE (0.40) CYP2C19PRKCEMYLKALDH1A1MEN1
SCHEMBL18184901 0.90 PRKCE (0.40) CYP2C19PRKCEMYLKALDH1A1MEN1
SCHEMBL10051862 0.90 ALOX15 (0.46) CYP2C19PRKCEMYLKALDH1A1MEN1
SCHEMBL18184902 0.90 ALOX15 (0.46) CYP2C19PRKCEMYLKALDH1A1MEN1
SCHEMBL2114143 0.89 CYP2C19 (0.55) CYP2C19PRKCEMYLKALDH1A1MEN1
SCHEMBL12133570 0.89 ALOX15 (0.45) CYP2C19PRKCEMYLKALDH1A1MEN1
SCHEMBL16451540 0.86 PRKCE (0.37) CYP2C19PRKCEMYLKALDH1A1MEN1
SCHEMBL14997929 0.84 PRKCE (0.36) CYP2C19PRKCEMYLKALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11815815-B2 Composition for forming silicon-containing resist underlayer film removable by wet process NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230350305-A1 MANUFACTURING METHOD FOR CURED SUBSTANCE, MANUFACTURING METHOD FOR LAMINATE, AND MANUFACTURING METHOD FOR SEMICONDUCTOR DEVICE, AND TREATMENT LIQUID FUJIFILM CORPORATION (JP) 2023-11-02 US disclosed
US-20230125270-A1 RADIATION SENSITIVE COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2023-04-27 US disclosed
US-20180181000-A1 RADIATION SENSITIVE COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-06-28 US disclosed
US-20180052391-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN COMPOSITION FILM, CURED PRODUCT, INSULATING FILM AND MULTILAYER WIRING BOARD TORAY INDUSTRIES, INC. (JP) 2018-02-22 US disclosed
US-20180039174-A1 PHOTOSENSITIVE RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2018-02-08 US disclosed
US-20170371242-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM REMOVABLE BY WET PROCESS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-12-28 US disclosed
US-20170334837-A1 DIAMINE COMPOUND, AND HEAT-RESISTANT RESIN OR HEAT-RESISTANT RESIN PRECURSOR USING SAME TORAY INDUSTRIES, INC. (JP) 2017-11-23 US disclosed
US-20170327644-A1 RESIN AND PHOTOSENSITIVE RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2017-11-16 US disclosed
US-9746772-B2 Resist underlayer film forming composition for lithography containing polyether structure-containing resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-08-29 US disclosed
US-20140235060-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION WHICH CONTAINS ALICYCLIC SKELETON-CONTAINING CARBAZOLE RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-08-21 US disclosed
US-8722841-B2 Carbazole novolak resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-05-13 US disclosed
US-8709552-B2 Resin composition and display device using the same TORAY INDUSTRIES, INC. (JP) 2014-04-29 US disclosed
US-8674052-B2 Carbazole novolak resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-03-18 US disclosed
US-20130280913-A1 COMPOSITION FOR FORMING A RESIST UNDERLAYER FILM INCLUDING HYDROXYL GROUP-CONTAINING CARBAZOLE NOVOLAC RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-10-24 US disclosed
US-20130189533-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION FOR LITHOGRAPHY CONTAINING POLYETHER STRUCTURE-CONTAINING RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-07-25 US disclosed
US-20130122710-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-05-16 US disclosed
US-8389649-B2 Siloxane-based resin composition TORAY INDUSTRIES, INC. (JP) 2013-03-05 US disclosed
US-20120077345-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-29 US disclosed
US-20110284855-A1 RESIN COMPOSITION AND DISPLAY DEVICE USING THE SAME TORAY INDUSTRIES, INC. (JP) 2011-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170334837-A1 DIAMINE COMPOUND, AND HEAT-RESISTANT RESIN OR HEAT-RESISTANT RESIN PRECURSOR USING SAME HEATR1, HSF1, RER1 CYP2C19 1610/4885PRKCE 3561/4885MYLK 4316/4885
US-20180181000-A1 RADIATION SENSITIVE COMPOSITION RER1, RAD1, RAD51 CYP2C19 1003/4885PRKCE 3408/4885MYLK 3497/4885
US-20230125270-A1 RADIATION SENSITIVE COMPOSITION XRCC6, RAD50, XRCC5 CYP2C19 418/4885PRKCE 2659/4885MYLK 3465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.