SCHEMBL1011491

SCHEMBL1011491

C1=CCC2Nc3ccccc3NC2=C1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 5/20 0.39
BRD4 O60885 4/20 0.39
EP300 Q09472 1/20 0.39
BRPF1 P55201 1/20 0.34
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3104456 0.78
SCHEMBL17146543 0.73 KDM4E (0.33) MEN1NPC1KMT2A
SCHEMBL12319503 0.73 KDM4E (0.33) MEN1NPC1KMT2A
SCHEMBL1899979 0.72
SCHEMBL7339316 0.72 ALDH1A1 (0.31)
SCHEMBL10064030 0.71 ALDH1A1 (0.33)
SCHEMBL25829886 0.69 ALDH1A1 (0.43) CREBBPBRD4MEN1NPC1KMT2A
SCHEMBL7612604 0.68 BRD4 (0.40) CREBBPBRD4
SCHEMBL31440970 0.68 GAA (0.38)
SCHEMBL20707954 0.68 NPC1 (0.40) MEN1NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105706260-B Compounds having a novel six-membered ring structure for use in organic electronic devices 默克专利有限公司 2019-08-13 CN claimed
US-10374167-B2 Compound with novel six-membered ring structure for use in organic electronic devices MERCK PATENT GMBH (DE) 2019-08-06 US claimed
CN-105706260-A Compounds having a novel six-membered ring structure for use in organic electronic devices 默克专利有限公司 2016-06-22 CN claimed
EP-2872501-A1 PYRIMIDINE PYRAZOLYL DERIVATIVES Ares Trading S.A. (CH) 2015-05-20 EP claimed
CN-103896831-A 4-(4-pyridinyl)-benzamides and their use as rock activity modulators ABBVIE DEUTSCHLAND 2014-07-02 CN claimed
WO-2014008992-A1 PYRIMIDINE PYRAZOLYL DERIVATIVES ARES TRADING S.A. (CH) 2014-01-16 WO claimed
US-3975379-A METHINE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 US claimed
US-11692065-B2 Phenazine copolymers and uses thereof CORNELL UNIVERSITY (US) 2023-07-04 US disclosed
CN-116209660-A Light-emitting element and composition 住友化学株式会社 2023-06-02 CN disclosed
CN-116209733-A Light-emitting element and composition 住友化学株式会社 2023-06-02 CN disclosed
CN-116194550-A Light-emitting element and composition 住友化学株式会社 2023-05-30 CN disclosed
CN-116194447-A Light-emitting element and composition 住友化学株式会社 2023-05-30 CN disclosed
US-11581495-B2 Phenyl derivatives substituted with at least two electron acceptors and at least two electron donors for use in organic electronic devices MERCK PATENT GMBH (DE) 2023-02-14 US disclosed
WO-1999023528-A2 ELECTROCHROMIC SYSTEM BAYER AKTIENGESELLSCHAFT (DE) 1999-05-14 WO disclosed
WO-1999009112-A1 UV-PROTECTED ELECTROCHROMIC SOLUTION BAYER AKTIENGESELLSCHAFT (DE) 1999-02-25 WO disclosed
WO-1999009111-A1 ELECTROCHROMIC SYSTEM WITH COUPLED RED-OX SYSTEM AND SPECIAL ANIONS BAYER AKTIENGESELLSCHAFT (DE) 1999-02-25 WO disclosed
EP-0880568-A1 ELECTROCHROMIC SYSTEM BAYER AG (DE) 1998-12-02 EP disclosed
WO-1998005737-A1 ELECTROCHROME SYSTEM BAYER AKTIENGESELLSCHAFT (DE) 1998-02-12 WO disclosed
WO-1997030134-A1 ELECTROCHROMIC SYSTEM BAYER AKTIENGESELLSCHAFT (DE) 1997-08-21 WO disclosed
US-3975379-A METHINE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10374167-B2 Compound with novel six-membered ring structure for use in organic electronic devices OCIAD2, OCIAD1, NR1D2 CREBBP 2794/4885BRD4 1527/4885EP300 2063/4885
US-11581495-B2 Phenyl derivatives substituted with at least two electron acceptors and at least two electron donors for use in organic electronic devices MAPRE2, MPC2, ETFB CREBBP 1606/4885BRD4 552/4885EP300 810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.