Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 9/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 14/20 | 0.65 |
| ▸ | MEN1 | O00255 | 13/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.62 |
| ▸ | USP2 | O75604 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | THRB | P10828 | 5/20 | 0.61 |
| ▸ | RECQL | P46063 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132708 | 1.00 | HTT (1.00) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL29499498 | 1.00 | HTT (1.00) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL132707 | 1.00 | HTT (1.00) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL29844163 | 1.00 | HTT (1.00) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL29844718 | 1.00 | HTT (1.00) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL21316089 | 0.89 | HTT (0.79) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL8439519 | 0.83 | HTT (0.71) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL13651755 | 0.83 | HTT (0.71) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL8439517 | 0.83 | HTT (0.71) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL11842646 | 0.82 | HTT (0.69) | HTTLMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655847-B | Preparation method of temperature-sensitive macromolecular dye, mascara containing temperature-sensitive macromolecular dye and preparation method of mascara | 浙江材华科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116655847-A | Preparation method of temperature-sensitive macromolecular dye, mascara containing temperature-sensitive macromolecular dye and preparation method of mascara | 浙江材华科技有限公司 | 2023-08-29 | — | — | CN | disclosed |
| US-11685741-B2 | Fluorescent probes | UNIVERSITY OF MASSACHUSETTS (US) | 2023-06-27 | — | — | US | disclosed |
| US-10961214-B2 | Small molecule lipid II inhibitors | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2021-03-30 | — | — | US | disclosed |
| US-10941114-B2 | Small molecule lipid II inhibitors | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2021-03-09 | — | — | US | disclosed |
| US-20200216394-A1 | Small Molecule Lipid II Inhibitors | UNIVERSITY OF MARYLAND, BALTIMORE | 2020-07-09 | — | — | US | disclosed |
| US-10435565-B2 | Methine dyes | LANXESS DEUTSCHLAND GMBH (DE) | 2019-10-08 | — | — | US | disclosed |
| US-10400274-B2 | Fluorogenic probes and their use in quantitative detection of target RNA sequences | JAN BIOTECH, INC. (US) | 2019-09-03 | — | — | US | disclosed |
| US-20190161618-A1 | NOVEL METHINE DYES | LANXESS DEUTSCHLAND GMBH (DE) | 2019-05-30 | — | — | US | disclosed |
| EP-3489228-A1 | NEW METHINE DYES | LANXESS Deutschland GmbH (DE) | 2019-05-29 | — | — | EP | disclosed |
| EP-1837182-B1 | Ink washing liquid and cleaning method | FUJIFILM CORP (JP) | 2010-05-12 | — | — | EP | disclosed |
| US-20090085017-A1 | COLORED CURABLE COMPOSITION, COLORED PATTERN AND COLOR FILTER USING THE SAME | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| EP-1955858-A1 | Undercoat solution, ink-jet recording method and ink-jet recording device | FUJIFILM Corporation (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-20080012887-A1 | Image forming method and image forming apparatus | FUJIFILM CORPORATION | 2008-01-17 | — | — | US | disclosed |
| EP-1876209-A1 | Ink composition, inkjet recording method, printed material, and process for producing lithographic printing plate | FUJIFILM Corporation (JP) | 2008-01-09 | — | — | EP | disclosed |
| US-20070281363-A1 | Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence | Terpetschnig, Ewald (US) | 2007-12-06 | — | — | US | disclosed |
| US-20070281363-A1 | Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence | Terpetschnig, Ewald (US) | 2007-12-06 | — | — | US | disclosed |
| CN-1043797-A | The visible sensitizers that is used for photopolymerizable composition | DU PONT (US) | 1990-07-11 | — | — | CN | disclosed |
| EP-0374875-A2 | Visible sensitizers for photopolymerizable compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |
| US-4917977-A | METHINE DYE, ETHYLENICALLY UNSATURATED COMPOUND AND FREE RADICAL GENERATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200216394-A1 | Small Molecule Lipid II Inhibitors | DBI, FABP2, HDLBP | HTT 4848/4885LMNA 1606/4885MAPT 2236/4885 |
| US-10941114-B2 | Small molecule lipid II inhibitors | DBI, FABP2, SREBF2 | HTT 4846/4885LMNA 1615/4885MAPT 2637/4885 |
| US-11685741-B2 | Fluorescent probes | FECH, CHERP, SLC40A1 | HTT 1835/4885LMNA 782/4885MAPT 2667/4885 |
| US-10961214-B2 | Small molecule lipid II inhibitors | DBI, FABP2, TMBIM6 | HTT 4879/4885LMNA 2417/4885MAPT 2577/4885 |
| US-20070281363-A1 | Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence | SPR, SRRT, SQLE | HTT 2663/4885LMNA 1873/4885MAPT 3790/4885 |
| US-10435565-B2 | Methine dyes | MB, PRMT5, TET3 | HTT 459/4885LMNA 2617/4885MAPT 896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.