SCHEMBL1011668

SCHEMBL1011668

NCc1ccc(-n2ccnc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.63
MAPT P10636 1/20 0.63
ENPP2 Q13822 1/20 0.58
MKNK1 Q9BUB5 1/20 0.58
MKNK2 Q9HBH9 1/20 0.58
NOTUM Q6P988 1/20 0.58
CYP3A4 P08684 4/20 0.57
LOXL2 Q9Y4K0 1/20 0.56
MEN1 O00255 1/20 0.55
ALOX15 P16050 1/20 0.55
TSHR P16473 1/20 0.55
KMT2A Q03164 1/20 0.55
TBXAS1 P24557 2/20 0.54
CYP2D6 P10635 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP19A1 P11511 2/20 0.50
BAZ2B Q9UIF8 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
CYP51A1 Q16850 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27516102 0.98 LMNA (0.61) LMNAMAPTENPP2MKNK1MKNK2
SCHEMBL5801060 0.85 LMNA (0.65) LMNAMAPTENPP2MKNK1MKNK2
SCHEMBL21791731 0.84 LMNA (0.62) LMNAMAPTENPP2MKNK1MKNK2
SCHEMBL2532397 0.83 LMNA (0.78) LMNAMAPTENPP2MKNK1MKNK2
SCHEMBL15750592 0.82 IDO1 (0.58) LMNAMAPTCYP3A4LOXL2MEN1
Hydrochloric Acid SCHEMBL28701756 0.81 LMNA (0.75) LMNAMAPTENPP2MKNK1MKNK2
SCHEMBL255498 0.81 MAOB (0.62) LMNAMAPTENPP2MKNK1MKNK2
SCHEMBL857216 0.81 ENPP2 (0.63) LMNAMAPTENPP2MKNK1MKNK2
SCHEMBL22486535 0.81 LMNA (0.58) LMNAMAPTENPP2MKNK1MKNK2
SCHEMBL2460217 0.81 NOTUM (0.63) LMNAMAPTENPP2MKNK1MKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117025125-B Flexible ultrathin conductive adhesive film and preparation method thereof 江苏特丽亮新材料科技有限公司 2024-02-20 CN claimed
CN-117025125-A Flexible ultrathin conductive adhesive film and preparation method thereof 江苏特丽亮新材料科技有限公司 2023-11-10 CN claimed
CN-114174293-A 4- (imidazo [1,2-a ] pyridin-3-yl) -pyrimidine derivatives 默克专利股份公司 2022-03-11 CN claimed
CN-105189494-B Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors 普罗克西梅根有限公司 2017-04-26 CN claimed
CN-102424671-B Synthesis method of 4-chloro-2-cyano-1-dimethylamino-sulfonyl-5-(4-methylphenyl)imidazo XIAN MODERN CHEMISTRY RES INST 2014-05-14 CN claimed
CN-117025125-B Flexible ultrathin conductive adhesive film and preparation method thereof 江苏特丽亮新材料科技有限公司 2024-02-20 CN disclosed
CN-117025125-B Flexible ultrathin conductive adhesive film and preparation method thereof 江苏特丽亮新材料科技有限公司 2024-02-20 CN disclosed
CN-117025125-A Flexible ultrathin conductive adhesive film and preparation method thereof 江苏特丽亮新材料科技有限公司 2023-11-10 CN disclosed
CN-117025125-A Flexible ultrathin conductive adhesive film and preparation method thereof 江苏特丽亮新材料科技有限公司 2023-11-10 CN disclosed
US-20220267320-A1 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL)-PYRIMIDINE DERIVATIVES MERCK PATENT GMBH (DE) 2022-08-25 US disclosed
CN-114174293-A 4- (imidazo [1,2-a ] pyridin-3-yl) -pyrimidine derivatives 默克专利股份公司 2022-03-11 CN disclosed
US-11186583-B2 5-alkylthio-7-[(4-arylbenzyl)amino]-1(2)H-pyrazolo[4,3-d]pyrimidines for treatment of lymphoma UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2021-11-30 US disclosed
US-20040209878-A1 Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors SCHERING CORPORATION AND PHARMACOPEIA, INC. 2004-10-21 US disclosed
WO-2004022561-A1 PYRAZOLOPYRIMIDINES AS CYCLIN-DEPENDENT KINASE INHIBITORS SCHERING CORPORATION (US) 2004-03-18 WO disclosed
EP-0358284-B1 Derivatized alkanolamines as cardiovascular agents SCHERING AG (DE) 1997-08-20 EP disclosed
CN-1016309-B BIOLOGICAL LETHAL AGENT COMPOSITION ISHIHARA SANGYO KAISHA (JP) 1992-04-22 CN disclosed
US-5051423-A Derivatized alkanolamines as cardiovascular agents SCHERING AG (DE) 1991-09-24 US disclosed
EP-0358284-A2 Derivatized alkanolamines as cardiovascular agents SCHERING AKTIENGESELLSCHAFT (DE) 1990-03-14 EP disclosed
WO-1990000548-A2 DERIVATIZED ALKANOLAMINES AS CARDIOVASCULAR AGENTS SCHERING AKTIENGESELLSCHAFT BERLIN AND BERGKAMEN (DE) 1990-01-25 WO disclosed
CN-88101228-A Imidazolium compounds and the biocides that contains this compound that is used for controlling harmful organism 1988-12-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220267320-A1 4-(IMIDAZO[1,2-A]PYRIDIN-3-YL)-PYRIMIDINE DERIVATIVES NCOA3, NCOR1, NCOA4 LMNA 3635/4885MAPT 4822/4885ENPP2 2145/4885
US-20040209878-A1 Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors CDK2, CDK1, CDK5 LMNA 2221/4885MAPT 3483/4885ENPP2 2063/4885
US-11186583-B2 5-alkylthio-7-[(4-arylbenzyl)amino]-1(2)H-pyrazolo[4,3-d]pyrimidines for treatment of lymphoma TK1, DCK, CCNK LMNA 2199/4885MAPT 4672/4885ENPP2 1793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.