Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624039 | 0.73 | PIK3CA (0.55) | PIK3CAPIK3CGALOX5CYP1A2AHR | |
| SCHEMBL13766486 | 0.66 | MAPT (0.44) | CYP1A2TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL3076222 | 0.66 | KDM4E (0.62) | PIK3CAPIK3CGALOX5CYP1A2PSMB8 | |
| SCHEMBL27568458 | 0.65 | ALOX5 (0.55) | ALOX5CYP1A2FAAHGRM5KDM4E | |
| SCHEMBL622482 | 0.63 | PIK3CG (0.80) | PIK3CAPIK3CGL3MBTL1MEN1LMNA | |
| SCHEMBL27623948 | 0.61 | ALOX5 (0.50) | ALOX5CYP1A2FAAHKDM4ELMNA | |
| SCHEMBL15128952 | 0.60 | KDM4E (0.48) | PIK3CAPIK3CGALOX5CYP1A1CYP1A2 | |
| SCHEMBL3589894 | 0.60 | ALDH1A1 (0.54) | ALOX5TDP1NPC1RAB9AFAAH | |
| SCHEMBL3055621 | 0.59 | ALOX5 (0.48) | ALOX5CYP1A2FAAHKDM4ELMNA | |
| Dipyridyl SCHEMBL27994607 | 0.59 | KDM4E (0.70) | CYP1A2TDP1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021707-A2 | PREMATURE-TERMINATION-CODONS READTHROUGH COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-16 | — | — | WO | disclosed |