SCHEMBL1011883

SCHEMBL1011883

Cc1cccc(C)c1P(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.52
CYP3A4 P08684 1/20 0.52
ACHE P22303 3/20 0.43
TSHR P16473 2/20 0.43
ESR1 P03372 3/20 0.41
ESR2 Q92731 3/20 0.41
CYP2A6 P11509 2/20 0.38
CYP1A2 P05177 1/20 0.38
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
DRD1 P21728 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
LMNA P02545 1/20 0.35
ALOX12 P18054 1/20 0.35
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20873230 0.87 TDP1 (0.44) TDP1CYP3A4ACHETSHRESR1
SCHEMBL19251642 0.85 CYP3A4 (0.42) TDP1CYP3A4ACHETSHRESR1
SCHEMBL20697881 0.85 TRPA1 (0.45) TDP1CYP3A4ACHETSHRESR1
SCHEMBL23182095 0.85 CYP3A4 (0.42) TDP1CYP3A4ACHETSHRESR1
SCHEMBL28294523 0.83 CYP3A4 (0.41) TDP1CYP3A4TSHRESR2CYP2A6
SCHEMBL21331888 0.82 CYP3A4 (0.44) TDP1CYP3A4ACHETSHRESR1
SCHEMBL20697880 0.82 CA1 (0.43) TDP1CYP3A4TSHRCYP1A2ALDH1A1
SCHEMBL3665710 0.82 TDP1 (0.39) TDP1CYP3A4ACHETSHRESR1
O-Xylene SCHEMBL5617302 0.81 CYP3A4 (0.71) TDP1CYP3A4ACHETSHRESR1
SCHEMBL7999830 0.81 TDP1 (0.48) TDP1CYP3A4ACHETSHRESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685755-B2 Dicarbonyl ruthenium and osmium catalysts Universita′ degli Studi di Udine (IT) 2023-06-27 US claimed
CN-108779041-B Ruthenium and osmium dicarbonyl catalysts 乌迪内大学 2022-05-13 CN claimed
EP-3411346-B1 DICARBONYL RUTHENIUM AND OSMIUM CATALYSTS UNIV DEGLI STUDI UDINE (IT) 2021-04-28 EP claimed
US-20210107929-A1 DICARBONYL RUTHENIUM AND OSMIUM CATALYSTS UNIVERSITA' DEGLI STUDI DI UDINE AND INNOVATION FACTORY S.R.L. (IT) 2021-04-15 US claimed
EP-3411346-A1 DICARBONYL RUTHENIUM AND OSMIUM CATALYSTS Universita' Degli Studi di Udine (IT) 2018-12-12 EP claimed
WO-2017134620-A1 DICARBONYL RUTHENIUM AND OSMIUM CATALYSTS UNIVERSITA' DEGLI STUDI DI UDINE (IT) 2017-08-10 WO claimed
US-11819837-B2 Monocarbonyl ruthenium and osmium catalysts UNIVERSITA DEGLI STUDI DI (IT) 2023-11-21 US disclosed
US-11685755-B2 Dicarbonyl ruthenium and osmium catalysts Universita′ degli Studi di Udine (IT) 2023-06-27 US disclosed
US-11685755-B2 Dicarbonyl ruthenium and osmium catalysts Universita′ degli Studi di Udine (IT) 2023-06-27 US disclosed
US-20230145668-A1 MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS UNIV DEGLI STUDI UDINE (IT) 2023-05-11 US disclosed
US-20230145668-A1 MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS UNIV DEGLI STUDI UDINE (IT) 2023-05-11 US disclosed
US-11577233-B2 Monocarbonyl ruthenium and osmium catalysts Universita' Delgi Studi Di Udine (IT) 2023-02-14 US disclosed
US-11577233-B2 Monocarbonyl ruthenium and osmium catalysts Universita' Delgi Studi Di Udine (IT) 2023-02-14 US disclosed
US-8357799-B2 Light emitting material SOLVAY (SOCIETE ANONYME) (BE) 2013-01-22 US disclosed
CN-102046642-A Hydroformylation catalysts EASTMAN CHEM CO 2011-05-04 CN disclosed
EP-2155764-B1 LIGHT EMITTING MATERIAL SOLVAY (BE) 2011-01-05 EP disclosed
CN-101808972-A Carbonylation process for the production of acetic acid using metal-pincer ligand catalysts BP CHEM INT LTD 2010-08-18 CN disclosed
US-20100190984-A1 Light emitting material SOLVAY (SOCIETE ANONYME) (BE) 2010-07-29 US disclosed
EP-2155764-A1 LIGHT EMITTING MATERIAL SOLVAY (Société Anonyme) (BE) 2010-02-24 EP disclosed
WO-2008148829-A1 LIGHT EMITTING MATERIAL Solvay (Société Anonyme) (BE) 2008-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11685755-B2 Dicarbonyl ruthenium and osmium catalysts OTC, ODC1, CBR3 TDP1 908/4885CYP3A4 2997/4885ACHE 2357/4885
US-20230145668-A1 MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS OTC, CBR3, IDH2 TDP1 3573/4885CYP3A4 2612/4885ACHE 2952/4885
US-11819837-B2 Monocarbonyl ruthenium and osmium catalysts OTC, CBR3, IDH2 TDP1 3573/4885CYP3A4 2612/4885ACHE 2952/4885
US-20100190984-A1 Light emitting material PPOX, CRY2, PIN4 TDP1 4501/4885CYP3A4 1580/4885ACHE 473/4885
US-20210107929-A1 DICARBONYL RUTHENIUM AND OSMIUM CATALYSTS OTC, ODC1, CBR3 TDP1 908/4885CYP3A4 2997/4885ACHE 2357/4885
US-11577233-B2 Monocarbonyl ruthenium and osmium catalysts OTC, CBR3, IDH2 TDP1 3573/4885CYP3A4 2612/4885ACHE 2952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.