Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.58 |
| ▸ | CTSS | P25774 | 4/20 | 0.58 |
| ▸ | CTSB | P07858 | 2/20 | 0.58 |
| ▸ | CTSV | O60911 | 2/20 | 0.58 |
| ▸ | GPR132 | Q9UNW8 | 7/20 | 0.57 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.54 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119250 | 0.88 | PSMB5 (0.65) | CTSLCTSSCTSBCTSKPSMB5 | |
| SCHEMBL7318555 | 0.88 | PSMB5 (0.65) | CTSLCTSSCTSBCTSKPSMB5 | |
| SCHEMBL14297659 | 0.87 | PSMB5 (0.56) | CTSLCTSSCTSBCTSVCTSK | |
| SCHEMBL10118950 | 0.87 | PSMB5 (0.56) | CTSLCTSSCTSBCTSVCTSK | |
| SCHEMBL12516880 | 0.87 | PSMB5 (0.56) | CTSLCTSSCTSBCTSVGPR132 | |
| SCHEMBL10659411 | 0.86 | GPR132 (0.72) | CTSLCTSSCTSBCTSVGPR132 | |
| SCHEMBL202770 | 0.85 | CTSL (0.60) | CTSLCTSSCTSBCTSVGPR132 | |
| SCHEMBL27547470 | 0.85 | CTSL (0.60) | CTSLCTSSCTSBCTSVGPR132 | |
| SCHEMBL10118994 | 0.85 | CTSB (0.51) | CTSLCTSSCTSBCTSVGPR132 | |
| SCHEMBL7315389 | 0.83 | PSMB5 (0.60) | CTSLCTSSCTSBCTSKPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |