Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980841 | 0.96 | CCNA2 (0.39) | CTSKMAPK8MAPK9MAPK10ALDH1A1 | |
| SCHEMBL19980889 | 0.89 | CCNA2 (0.38) | CTSKMAPK8MAPK9MAPK10ALDH1A1 | |
| SCHEMBL19657288 | 0.78 | CTSK (0.46) | CTSKMAPK8MAPK9MAPK10ALDH1A1 | |
| SCHEMBL21278104 | 0.77 | CTSK (0.46) | CTSKMAPK8MAPK9MAPK10ALDH1A1 | |
| SCHEMBL21277953 | 0.74 | ALDH1A1 (0.60) | CTSKMAPK8MAPK9MAPK10ALDH1A1 | |
| SCHEMBL21277906 | 0.74 | ALDH1A1 (0.60) | CTSKMAPK8MAPK9MAPK10ALDH1A1 | |
| SCHEMBL10119018 | 0.73 | TP53 (0.35) | ALDH1A1TP53THRB | |
| SCHEMBL21278057 | 0.68 | ALDH1A1 (0.58) | MAPK8MAPK9MAPK10ALDH1A1HPGD | |
| SCHEMBL19980923 | 0.67 | POLB (0.45) | ALDH1A1HPGDKDM4EGAAHSD17B10 | |
| SCHEMBL11295972 | 0.66 | THRB (0.40) | ALDH1A1TP53THRBTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |