Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980892 | 0.96 | CTSK (0.42) | CCNA2CDK2CCNA1EGFRTHRB | |
| SCHEMBL10119018 | 0.77 | TP53 (0.35) | THRBTP53ALDH1A1 | |
| SCHEMBL10119233 | 0.71 | TP53 (0.30) | THRBTP53ALDH1A1 | |
| SCHEMBL21278104 | 0.71 | CTSK (0.46) | CCNA2CDK2CCNA1EGFRMAPK8 | |
| SCHEMBL19980923 | 0.70 | POLB (0.45) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL11295972 | 0.69 | THRB (0.40) | THRBTP53ALDH1A1GLATDP1 | |
| SCHEMBL21277953 | 0.68 | ALDH1A1 (0.60) | TP53MAPK8CTSKALDH1A1HPGD | |
| SCHEMBL21277906 | 0.68 | ALDH1A1 (0.60) | TP53MAPK8CTSKALDH1A1HPGD | |
| SCHEMBL29096365 | 0.65 | THRB (0.47) | THRBALDH1A1TDP1TSHR | |
| SCHEMBL9683157 | 0.64 | THRB (0.40) | THRBALDH1A1KDM4EKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785797-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |