Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.61 |
| ▸ | CTSS | P25774 | 6/20 | 0.61 |
| ▸ | CTSB | P07858 | 3/20 | 0.61 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | GRN | P28799 | 1/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.50 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.48 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.48 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.48 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | LONP1 | P36776 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119265 | 0.90 | CTSS (0.69) | CTSLCTSSCTSBCTSKGRN | |
| SCHEMBL10118973 | 0.86 | CTSS (0.62) | CTSLCTSSCTSBCTSKGRN | |
| SCHEMBL10118853 | 0.84 | CTSL (0.55) | CTSLCTSSCTSBCTSKGRN | |
| SCHEMBL5528491 | 0.83 | CTSL (0.81) | CTSLCTSSCTSBCTSKCHRNB2 | |
| SCHEMBL10118950 | 0.76 | PSMB5 (0.56) | CTSLCTSSCTSBCTSKPSMB5 | |
| SCHEMBL14297659 | 0.76 | PSMB5 (0.56) | CTSLCTSSCTSBCTSKPSMB5 | |
| SCHEMBL5528488 | 0.76 | CTSL (0.62) | CTSLCTSSCTSBCTSKGRN | |
| SCHEMBL5131090 | 0.75 | CA2 (0.57) | — | |
| SCHEMBL2917517 | 0.75 | CA2 (0.57) | — | |
| SCHEMBL2917519 | 0.75 | CA2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |