Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.69 |
| ▸ | CTSL | P07711 | 10/20 | 0.69 |
| ▸ | CTSB | P07858 | 3/20 | 0.69 |
| ▸ | CTSK | P43235 | 1/20 | 0.69 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.58 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.58 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.58 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.58 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.57 |
| ▸ | GRN | P28799 | 1/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.53 |
| ▸ | CTSV | O60911 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10118973 | 0.94 | CTSS (0.62) | CTSSCTSLCTSBCTSKCHRNB2 | |
| SCHEMBL10119214 | 0.90 | CTSL (0.61) | CTSSCTSLCTSBCTSKCHRNB2 | |
| SCHEMBL18127223 | 0.86 | GRN (0.69) | CTSSCTSLCTSBCTSKCHRNB2 | |
| SCHEMBL10119287 | 0.85 | CTSS (0.60) | CTSSCTSLCTSBCTSKCHRNB2 | |
| SCHEMBL12831363 | 0.84 | CTSL (0.70) | CTSSCTSLCTSBCTSKCHRNB2 | |
| SCHEMBL5529226 | 0.82 | CTSS (0.72) | CTSSCTSLCTSBCTSKCHRNB2 | |
| SCHEMBL5525339 | 0.82 | CTSL (1.00) | CTSSCTSLCTSBCTSKCHRNB2 | |
| SCHEMBL6867271 | 0.82 | CTSL (1.00) | CTSSCTSLCTSBCTSKCHRNB2 | |
| SCHEMBL5530445 | 0.82 | CTSL (1.00) | CTSSCTSLCTSBCTSKCHRNB2 | |
| SCHEMBL6875796 | 0.82 | CTSL (1.00) | CTSSCTSLCTSBCTSKCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |