Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 5/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10118862 | 0.86 | PSMB5 (0.56) | CTSBCTSSPSMB5CTSL | |
| SCHEMBL10118970 | 0.86 | PSMB5 (0.56) | CTSBCTSSPSMB5CTSL | |
| SCHEMBL10119207 | 0.84 | MMP9 (0.55) | MMP9MMP14CTSBMMEALDH1A1 | |
| SCHEMBL10118849 | 0.84 | HPGD (0.56) | CTSBSMN1; SMN2HPGDPSMB5CTSL | |
| SCHEMBL10118845 | 0.81 | CTSB (0.52) | CTSBMMECTSSPSMB5CTSL | |
| SCHEMBL10118851 | 0.81 | CTSB (0.52) | CTSBMMECTSSPSMB5CTSL | |
| SCHEMBL10118811 | 0.81 | CTSB (0.57) | CTSBCTSSPSMB5CTSL | |
| SCHEMBL10118869 | 0.79 | PSMB5 (0.48) | CTSBCTSSPSMB5CTSL | |
| SCHEMBL10118968 | 0.79 | CTSL (0.50) | CTSBCTSSPSMB5CTSL | |
| SCHEMBL10118859 | 0.79 | CTSL (0.51) | CTSBCTSSPSMB5CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |