Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16418003 | 0.85 | FOLH1 (0.63) | MMEPPARAPPARGFOLH1CTSL | |
| SCHEMBL20637864 | 0.85 | FOLH1 (0.63) | MMEPPARAPPARGFOLH1CTSL | |
| SCHEMBL18127216 | 0.85 | FOLH1 (0.63) | MMEPPARAPPARGFOLH1CTSL | |
| SCHEMBL10119290 | 0.84 | MMP9 (0.47) | MMP9MMP14MMEPPARAPPARG | |
| SCHEMBL10119250 | 0.83 | PSMB5 (0.65) | MMECTSBCTSSPSMB5CTSL | |
| SCHEMBL7318555 | 0.83 | PSMB5 (0.65) | MMECTSBCTSSPSMB5CTSL | |
| SCHEMBL7330223 | 0.82 | PPARA (0.71) | MMP9MMP14MMEPPARAPPARG | |
| SCHEMBL5525872 | 0.81 | CTSL (0.71) | CTSBCTSSCTSLCTSK | |
| SCHEMBL10119210 | 0.81 | HPGD (0.63) | CTSSPSMB5CTSLCTSKSMN1; SMN2 | |
| SCHEMBL7323154 | 0.80 | PPARA (0.69) | MMP9MMP14PPARAPPARGCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004554-A1 | ALDEHYDE COMPOUNDS AS INHIBITORS OF DUST MITE GROUP 1 PEPTIDASE ALLERGEN AND THEIR USE | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2012-01-12 | — | — | WO | disclosed |