Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119912 | 0.87 | HTT (0.52) | MAOAALDH1A1HTTTSHRKDM4E | |
| SCHEMBL10957254 | 0.80 | ALDH1A1 (0.55) | MAOAALDH1A1HTTTSHRKDM4E | |
| SCHEMBL12154389 | 0.78 | LMNA (0.48) | MAOAALDH1A1HTTTSHRKDM4E | |
| SCHEMBL14434321 | 0.75 | MAPT (0.57) | ALDH1A1HTTTSHRKDM4EPOLB | |
| SCHEMBL14319793 | 0.74 | MAOA (0.44) | MAOACYP3A4LMNAMEN1KMT2A | |
| SCHEMBL10119656 | 0.73 | SLC6A4 (0.69) | HTTMAPTCYP3A4LMNAMEN1 | |
| SCHEMBL725448 | 0.72 | MAPT (0.61) | ALDH1A1HTTTSHRKDM4EPOLB | |
| SCHEMBL6946412 | 0.70 | PRMT5 (0.60) | MAOACYP3A4MEN1KMT2APRMT5 | |
| SCHEMBL14286564 | 0.69 | EP300 (0.42) | MAOACYP3A4MEN1KMT2APRMT5 | |
| SCHEMBL10782763 | 0.68 | NPC1 (0.64) | MAOAALDH1A1HTTPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781639-B1 | SUBSTITUTED INDOLYL ALKYL AMINO DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | JANSSEN PHARMACEUTICA NV (BE) | 2012-01-25 | — | — | EP | disclosed |