SCHEMBL1011992

SCHEMBL1011992

CCCCCCCCCCCCn1cncc1C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 1/20 0.43
QPCT Q16769 11/20 0.43
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
TLR8 Q9NR97 2/20 0.41
CYP19A1 P11511 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
POLB P06746 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28220941 1.00 TBXAS1 (0.43) TBXAS1QPCTCYP3A4CYP2D6CYP2C9
SCHEMBL9822957 1.00 TBXAS1 (0.43) TBXAS1QPCTCYP3A4CYP2D6CYP2C9
SCHEMBL8591844 0.98 QPCT (0.43) TBXAS1QPCTCYP3A4CYP2D6CYP2C9
SCHEMBL329374 0.92 ALDH1A1 (0.46) QPCTCYP3A4CYP2D6CYP2C9ALDH1A1
Pyrazole SCHEMBL9626094 0.84 QPCT (0.40) TBXAS1QPCTCYP3A4CYP2D6CYP2C9
SCHEMBL5657481 0.84
SCHEMBL3626809 0.81 QPCT (0.44) QPCTCYP19A1CYP11B1CYP11B2
SCHEMBL9783063 0.80 KDM4E (0.40) TBXAS1QPCTCYP2D6ALDH1A1TLR8
SCHEMBL9783071 0.79 TLR8 (0.38) QPCTTLR8
SCHEMBL3815545 0.78 QPCT (0.64) QPCT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1960345-B1 ALKYLATION OF N' -PHENYL-N-ALKYLPHENYLENEDIAMINES IN IONIC LIQUID, AND N' -PHENYL-N-ALKYL(ALKYLPHENYLENE) DIAMINES PRODUCED THEREBY CHEMTURA CORP (US) 2014-11-19 EP claimed
CN-101336225-B Alkylation of n' -phenyl-n-alkylphenylenediamines in ionic liquid, n' -phenyl-n-alkyl(alkylphenylene) diamines produced thereby, and lubricant compositions containing same CHEMTURA CORP 2012-02-29 CN claimed
CN-101336224-B Ring alkylation of aniline or an aniline derivative using ionic liquid catalysts CHEMTURA CORP 2011-09-14 CN claimed
CN-101336223-B Alkylation of a diphenylamine compound in ionic liquid CHEMTURA CORP 2011-09-14 CN claimed
EP-1963253-B1 RING ALKYLATION OF ANILINE OR AN ANILINE DERIVATIVE USING IONIC LIQUID CATALYSTS CHEMTURA CORP (US) 2011-01-05 EP claimed
EP-1960344-B1 ALKYLATION OF A DIPHENYLAMINE COMPOUND IN IONIC LIQUID CHEMTURA CORP (US) 2010-09-29 EP claimed
US-7563929-B2 Alkylation of N′-phenyl-N-alkylphenylenediamines in ionic liquid and N′-phenyl-N-alkyl(alkylphenylene) diamines produced thereby CHEMTURA CORPORATION (US) 2009-07-21 US claimed
CN-101336225-A Alkylation of n' -phenyl-n-alkylphenylenediamines in ionic liquid, n' -phenyl-n-alkyl(alkylphenylene) diamines produced thereby, and lubricant compositions containing same CHEMTURA CORP (US) 2008-12-31 CN claimed
CN-101336224-A Ring alkylation of aniline or an aniline derivative using ionic liquid catalysts CHEMTURA CORP (US) 2008-12-31 CN claimed
CN-101336223-A Alkylation of a diphenylamine compound in ionic liquid CHEMTURA CORP (US) 2008-12-31 CN claimed
EP-1963253-A2 RING ALKYLATION OF ANILINE OR AN ANILINE DERIVATIVE USING IONIC LIQUID CATALYSTS CHEMTURA CORPORATION (US) 2008-09-03 EP claimed
EP-1960345-A1 ALKYLATION OF N' -PHENYL-N-ALKYLPHENYLENEDIAMINES IN IONIC LIQUID, N' -PHENYL-N-ALKYL(ALKYLPHENYLENE) DIAMINES PRODUCED THEREBY, AND LUBRICANT COMPOSITIONS CONTAINING SAME CHEMTURA CORPORATION (US) 2008-08-27 EP claimed
EP-1960344-A1 ALKYLATION OF A DIPHENYLAMINE COMPOUND IN IONIC LIQUID CHEMTURA CORPORATION (US) 2008-08-27 EP claimed
US-7378554-B2 Ring alkylation of aniline or an aniline derivative using ionic liquid catalysts CHEMTURA CORPORATION (US) 2008-05-27 US claimed
WO-2007070264-A1 ALKYLATION OF A DIPHENYLAMINE COMPOUND IN IONIC LIQUID CHEMTURA CORPORATION (US) 2007-06-21 WO claimed
WO-2007070282-A1 ALKYLATION OF N' -PHENYL-N-ALKYLPHENYLENEDIAMINES IN IONIC LIQUID, N' -PHENYL-N-ALKYL(ALKYLPHENYLENE) DIAMINES PRODUCED THEREBY, AND LUBRICANT COMPOSITIONS CONTAINING SAME CHEMTURA CORPORATION (US) 2007-06-21 WO claimed
WO-2007070263-A2 RING ALKYLATION OF ANILINE OR AN ANILINE DERIVATIVE USING IONIC LIQUID CATALYSTS CHEMTURA CORPORATION (US) 2007-06-21 WO claimed
US-20070135656-A1 Ring alkylation of aniline or an aniline derivative using ionic liquid catalysts LANXESS SOLUTIONS US INC. 2007-06-14 US claimed
US-20070135657-A1 Alkylation of N'-phenyl-N-alkylphenylenediamines in ionic liquid, N'-phenyl-N-alkyl (alkylphenylene) diamines produced thereby, and lubricant compositions containing same LANXESS SOLUTIONS US INC. 2007-06-14 US claimed
US-7145038-B1 Alkylation of a diphenylamine compound in ionic liquid CHEMTURA CORPORATION (US) 2006-12-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135657-A1 Alkylation of N'-phenyl-N-alkylphenylenediamines in ionic liquid, N'-phenyl-N-alkyl (alkylphenylene) diamines produced thereby, and lubricant compositions containing same NAPEPLD, PNN, ACR TBXAS1 3345/4885QPCT 1834/4885CYP3A4 861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.