Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37664 | 0.85 | HTR2A (0.62) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL37665 | 0.84 | AKR1C3 (0.62) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL6399778 | 0.84 | IDO1 (0.59) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL9676461 | 0.83 | TSHR (0.56) | IDO1AKR1C3ALDH1A1CYP2C19 | |
| SCHEMBL11161827 | 0.83 | HTR2A (0.57) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL10751236 | 0.83 | RAB9A (0.54) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL17128295 | 0.82 | IDO1 (0.58) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL4725847 | 0.82 | HTR2A (0.59) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL11099610 | 0.82 | IDO1 (0.58) | IDO1RAB9AAKR1C3HTTHTR2A | |
| SCHEMBL1555636 | 0.82 | ALDH1A1 (0.59) | IDO1RAB9AAKR1C3HTTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435352-A2 | 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines | Wyeth Holdings Corporation (US) | 2004-07-07 | — | — | EP | claimed |
| EP-0618190-B1 | 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines | WYETH CORP (US) | 2004-05-19 | — | — | EP | claimed |
| EP-0639585-A1 | Elastase inhibitor | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | claimed |
| US-5371076-A | ANTIBIOTICS | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | claimed |
| EP-0618190-A1 | 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1994-10-05 | — | — | EP | claimed |
| EP-0181702-B1 | 6-SUBSTITUTED PENICILLANIC ACID 1,1-DIOXIDE COMPOUNDS | PFIZER INC. (US) | 1989-05-31 | — | — | EP | claimed |
| EP-0083484-B1 | 1,1-ALKANEDIOL DICARBOXYLATE LINKED ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 1986-02-19 | — | — | EP | claimed |
| EP-0082666-B1 | BIS-HYDROXYMETHYL CARBONATE BRIDGED ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 1986-02-05 | — | — | EP | claimed |
| EP-0060119-B1 | AZETIDINONE COMPOUNDS AND THEIR PREPARATION | ELI LILLY AND COMPANY (US) | 1985-04-10 | — | — | EP | claimed |
| US-4461726-A | Desulfurization of penicillins to prepare azetidinones | HOFFMANN-LA ROCHE INC. (US) | 1984-07-24 | — | — | US | claimed |
| EP-0079167-A1 | A carbapenem compound, preparation and use | BEECHAM GROUP PLC (GB) | 1983-05-18 | — | — | EP | claimed |
| US-4359472-A | DERIVED FROM A PENICILLIN AND A BETA-LACTAMASE INHIBITOR | PFIZER INC. (US) | 1982-11-16 | — | — | US | claimed |
| US-4352752-A | Process for the preparation of dipeptides | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1982-10-05 | — | — | US | claimed |
| EP-0060119-A1 | Azetidinone compounds and their preparation | ELI LILLY AND COMPANY (US) | 1982-09-15 | — | — | EP | claimed |
| US-4347181-A | Intermediates for producing bicyclic β-lactam-antibiotics | BEECHAM GROUP LIMITED (GB) | 1982-08-31 | — | — | US | claimed |
| US-4289696-A | BETA-LACTAMASE INHIBITORY AGENTS WHICH ENHANCE ACTIVITY OF A PENICICILLIN OR CEPHALOSPORIN | BEECHAM GROUP LIMITED (GB) | 1981-09-15 | — | — | US | claimed |
| EP-0024832-A1 | Beta-lactam antibiotics, their preparation, pharmaceutical compositions containing them and their preparation | BEECHAM GROUP PLC (GB) | 1981-03-11 | — | — | EP | claimed |
| US-4048163-A | Process for preparation of 7-alkoxy-3-chloromethylcephems | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | claimed |
| US-4042585-A | Process for preparation of 3-halomethylcephems | ELI LILLY AND COMPANY (US) | 1977-08-16 | — | — | US | claimed |
| US-4012380-A | 7-Acylamino-3-acyl-2(or 3)cephems | ELI LILLY AND COMPANY (US) | 1977-03-15 | — | — | US | claimed |