Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 13/20 | 0.47 |
| ▸ | MEN1 | O00255 | 10/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 10/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10120120 | 0.89 | MAPT (0.53) | TERTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18780317 | 0.85 | MAPT (0.50) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10120137 | 0.79 | CA1 (0.45) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6934242 | 0.79 | RAB9A (0.61) | TERTMAPTMEN1KMT2ALMNA | |
| SCHEMBL10120119 | 0.79 | CA1 (0.46) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2286199 | 0.78 | CA12 (0.53) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2286201 | 0.78 | CA12 (0.53) | MAPTMEN1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6930371 | 0.77 | CA1 (0.59) | TERTMAPTMEN1KMT2ALMNA | |
| SCHEMBL11573347 | 0.76 | TERT (0.58) | TERTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2281399 | 0.76 | TP53 (0.60) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9629911-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-04-25 | — | — | US | disclosed |
| US-20150224193-A1 | PHOTOREACTIVE REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-08-13 | — | — | US | disclosed |
| US-9097707-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130137113-A1 | Photoreactive Regulator of Protein Function and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-30 | — | — | US | disclosed |
| US-8309350-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-13 | — | — | US | disclosed |
| US-20120190094-A1 | Photoreactive Regulator of Protein Function and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-07-26 | — | — | US | disclosed |
| US-8114843-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-14 | — | — | US | disclosed |
| US-8114843-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-14 | — | — | US | disclosed |
| US-20070128662-A1 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-06-07 | — | — | US | disclosed |
| US-20070128662-A1 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150224193-A1 | PHOTOREACTIVE REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF | PPP1R10, PPP6R3, ANKRD52 | TERT 4545/4885MAPT 4329/4885MEN1 3146/4885 |
| US-20070128662-A1 | Photoreactive regulator of protein function and methods of use thereof | PPP1R10, PPP6R3, ANKRD52 | TERT 4545/4885MAPT 4329/4885MEN1 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.