Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10120711 | 0.89 | KDM4E (0.53) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL12802790 | 0.88 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL11756039 | 0.86 | TSHR (0.48) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL28005220 | 0.85 | TUBB4A (0.52) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL11752347 | 0.84 | L3MBTL1 (0.43) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL10120710 | 0.83 | KDM4E (0.53) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL10120487 | 0.83 | KDM4E (0.59) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL11754271 | 0.81 | TSHR (0.48) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL28005576 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL11565793 | 0.81 | TP53 (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006068-A2 | COMPOUNDS FOR THE INHIBITION OF CELLULAR PROLIFERATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-01-12 | — | — | WO | disclosed |