Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11756039 | 0.94 | TSHR (0.48) | TSHRL3MBTL1MAPK1MEN1LMNA | |
| SCHEMBL11754747 | 0.93 | L3MBTL1 (0.48) | TSHRL3MBTL1MAPK1MEN1LMNA | |
| SCHEMBL11753074 | 0.90 | L3MBTL1 (0.57) | TSHRL3MBTL1MAPK1MEN1LMNA | |
| SCHEMBL11753935 | 0.86 | L3MBTL1 (0.43) | TSHRL3MBTL1MAPK1MEN1LMNA | |
| SCHEMBL11747878 | 0.84 | L3MBTL1 (0.57) | TSHRL3MBTL1MAPK1MEN1LMNA | |
| SCHEMBL11564594 | 0.83 | TP53 (0.47) | TSHRL3MBTL1MAPK1MEN1LMNA | |
| SCHEMBL11751223 | 0.82 | ALOX5 (0.58) | MEN1LMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL11751772 | 0.82 | ALOX5 (0.58) | MEN1LMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL11752347 | 0.81 | L3MBTL1 (0.43) | TSHRL3MBTL1MAPK1MEN1LMNA | |
| SCHEMBL10120709 | 0.81 | ALDH1A1 (0.50) | TSHRL3MBTL1MAPK1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |