Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 9/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012712 | 0.85 | KMT2A (0.39) | KDM4EHSD17B10ALDH1A1ITGA4ITGB7 | |
| SCHEMBL1396765 | 0.84 | KDM4E (0.36) | KDM4EHPGDHSD17B10ALDH1A1ITGA4 | |
| SCHEMBL4801263 | 0.75 | CYP1A2 (0.40) | KDM4EHPGDHSD17B10ALDH1A1GAA | |
| SCHEMBL1012752 | 0.70 | KMT2A (0.39) | KDM4EHSD17B10ALDH1A1CUL4AMEN1 | |
| SCHEMBL1013267 | 0.69 | ITGA4 (0.32) | KDM4EALDH1A1ITGA4ITGB7HTT | |
| SCHEMBL27956205 | 0.69 | CFD (0.33) | KDM4EHPGDHSD17B10ALDH1A1ITGA4 | |
| SCHEMBL1015004 | 0.68 | KMT2A (0.36) | KDM4EHPGDHSD17B10ALDH1A1GAA | |
| SCHEMBL4799225 | 0.66 | NPC1 (0.45) | KDM4EHPGDALDH1A1HTTMAPT | |
| SCHEMBL8795182 | 0.65 | MAPT (0.44) | KDM4EHPGDHSD17B10ALDH1A1GAA | |
| SCHEMBL5696330 | 0.65 | CYP11B2 (0.31) | KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678119-B1 | METHOD FOR PRODUCING 2-DIHALOACYL-3-AMINO-ACRYLIC ACID ESTERS AND 3-DIHALOMETHYL-PYRAZOLE-4-CARBOXYLIC ACID ESTERS | BAYER CROPSCIENCE AG (DE) | 2011-01-05 | — | — | EP | disclosed |