SCHEMBL1012238

SCHEMBL1012238

CCCCOC(O)OC.Nc1nc(N)nc(N)n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 3/20 0.36
CCNB1 P14635 3/20 0.36
CCNA2 P20248 2/20 0.36
CDK2 P24941 2/20 0.36
CCNA1 P78396 2/20 0.36
PIN1 Q13526 1/20 0.36
LMNA P02545 2/20 0.34
HTT P42858 2/20 0.34
HSD17B10 Q99714 1/20 0.34
HRH2 P25021 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
PDE4D Q08499 1/20 0.33
KCNH2 Q12809 2/20 0.32
DNM1 Q05193 1/20 0.32
TLR8 Q9NR97 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8866099 0.84
SCHEMBL195696 0.75 HTR7 (0.34) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL8214121 0.74 TLR8 (0.42) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL9613742 0.73 KCNH2 (0.34) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL808427 0.73 TSHR (0.42) HTTHSD17B10CYP3A4TSHRDNM1
Methoxymethane SCHEMBL6774591 0.72 TSHR (0.44) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL8601291 0.72 KCNH2 (0.38) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL9769720 0.72 TSHR (0.48) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL16423542 0.72 CDK1 (0.38) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL5156866 0.70 CDK1 (0.35) CDK1CCNB1CCNA2CDK2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1482014-B1 Coating film formation process and coated article HONDA MOTOR CO LTD (JP) 2011-01-05 EP disclosed
US-20040241450-A1 Coating film formation process and coated article HONDA MOTOR CO., LTD. 2004-12-02 US disclosed
EP-1482014-A1 Coating film formation process and coated article HONDA MOTOR CO., Ltd. (JP) 2004-12-01 EP disclosed