SCHEMBL10122600

SCHEMBL10122600

c1ccc2cc(-c3c4ccccc4c(-c4ccc5oc6ccc(-c7c8ccccc8cc8c7oc7ccccc78)cc6c5c4)c4ccccc34)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.39
RAB9A P51151 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2C9 P11712 1/20 0.39
MAPT P10636 3/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GPR84 Q9NQS5 1/20 0.38
ALOX5 P09917 2/20 0.37
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
CASP3 P42574 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
AHR P35869 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20127368 0.96 GPR84 (0.40) NPC1RAB9ACYP1A2CYP2C19CYP2C9
SCHEMBL10122594 0.95 GPR84 (0.41) NPC1RAB9ACYP1A2CYP2C19CYP2C9
SCHEMBL10122669 0.93 CYP1B1 (0.40) NPC1RAB9ACYP1A2CYP2C19CYP2C9
SCHEMBL10122577 0.93 GPR84 (0.40) NPC1RAB9ACYP1A2CYP2C19CYP2C9
SCHEMBL20127359 0.92 GPR84 (0.40) NPC1RAB9ACYP1A2CYP2C19CYP2C9
SCHEMBL10122682 0.92 GPR84 (0.39) NPC1RAB9ACYP1A2CYP2C19CYP2C9
SCHEMBL10122381 0.92 MAPT (0.41) NPC1RAB9ACYP1A2CYP2C19CYP2C9
SCHEMBL10122597 0.92 GPR84 (0.39) NPC1RAB9ACYP1A2CYP2C19CYP2C9
SCHEMBL10122692 0.92 GPR84 (0.39) NPC1RAB9ACYP1A2CYP2C19CYP2C9
SCHEMBL20127362 0.91 PIK3CD (0.40) NPC1RAB9ACYP1A2CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-9373792-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-06-21 US disclosed
US-9373792-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-06-21 US disclosed
US-9312500-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2016-04-12 US disclosed
US-9312500-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2016-04-12 US disclosed
US-20150372237-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2015-12-24 US disclosed
US-20150372237-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2015-12-24 US disclosed
US-20150005512-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-01-01 US disclosed
US-8866135-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-10-21 US disclosed
US-8866135-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-10-21 US disclosed
US-20140159005-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IIDEMITSU KOSAN CO., LTD (JP) 2014-06-12 US disclosed
US-20140159005-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IIDEMITSU KOSAN CO., LTD (JP) 2014-06-12 US disclosed
US-20140061622-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-03-06 US disclosed
US-8629430-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-01-14 US disclosed
US-8629430-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-01-14 US disclosed
US-20120138914-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20120138914-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 NPC1 1202/4885RAB9A 2163/4885CYP1A2 821/4885
US-20140159005-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SOX18, ANXA1, ANXA11 NPC1 3240/4885RAB9A 1969/4885CYP1A2 180/4885
US-20150372237-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SOX18, ANXA1, ANXA11 NPC1 3240/4885RAB9A 1969/4885CYP1A2 180/4885
US-20120138914-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SOX18, ANXA1, ANXA11 NPC1 3240/4885RAB9A 1969/4885CYP1A2 180/4885
US-20150005512-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SOX18, ANXA1, ANXA11 NPC1 3240/4885RAB9A 1969/4885CYP1A2 180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.