SCHEMBL20127362

SCHEMBL20127362

c1ccc(-c2ccc(-c3c4ccccc4cc4c3oc3ccc(-c5c6ccccc6c(-c6ccc7ccccc7c6)c6ccccc56)cc34)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 2/20 0.40
XRCC6 P12956 2/20 0.40
XRCC5 P13010 2/20 0.40
PRKDC P78527 2/20 0.40
PIK3CA P42336 1/20 0.40
GPR84 Q9NQS5 4/20 0.40
ESR1 P03372 3/20 0.38
ESR2 Q92731 3/20 0.38
PGR P06401 1/20 0.38
PLA2G2A P14555 1/20 0.36
PLA2G4A P47712 1/20 0.36
ALOX5 P09917 1/20 0.36
KDM4E B2RXH2 3/20 0.36
HSD17B10 Q99714 3/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
TSHR P16473 2/20 0.36
GLA P06280 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20127359 0.99 GPR84 (0.40) PIK3CDXRCC6XRCC5PRKDCPIK3CA
SCHEMBL20127368 0.95 GPR84 (0.40) PIK3CDXRCC6XRCC5PRKDCPIK3CA
SCHEMBL20127401 0.94 PGR (0.40) PIK3CDXRCC6XRCC5PRKDCPIK3CA
SCHEMBL24119018 0.93 PIK3CD (0.43) PIK3CDXRCC6XRCC5PRKDCPIK3CA
SCHEMBL10122600 0.91 NPC1 (0.39) PIK3CDXRCC6XRCC5PRKDCPIK3CA
SCHEMBL10122597 0.91 GPR84 (0.39) PIK3CDXRCC6XRCC5PRKDCPIK3CA
SCHEMBL17944498 0.91 PIK3CD (0.42) PIK3CDXRCC6XRCC5PRKDCPIK3CA
SCHEMBL20131253 0.91 ESR1 (0.36) PIK3CDXRCC6XRCC5PRKDCPIK3CA
SCHEMBL26269050 0.90 PIK3CD (0.38) PIK3CDXRCC6XRCC5PRKDCPIK3CA
SCHEMBL20127367 0.90 ESR1 (0.41) PIK3CDXRCC6XRCC5PRKDCPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 PIK3CD 4518/4885XRCC6 2689/4885XRCC5 2733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.